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Table 3 Comparison of the characteristics of men with Corynebacterium-dominated and non-Corynebacterium-dominated penile microbiota

From: The penile microbiota of Black South African men: relationship with human papillomavirus and HIV infection

CharacteristicCorynebacterium-dominated microbiota (CST-1)
(N = 127)
Non-Corynebacterium-dominated microbiota(CSTs2–6)
(N = 111)
p-value#
Age (years)37.0 (31.0–44.0)36.0 (30.0–44.0)0.597
Age at sexual debut (years)a17.0 (15.0–18.0)16.0 (15.0–18.0)0.975
Number of lifetime sexual partners6.0 (3.0–12.0)7.0 (3.0–14.0)0.693
Number of sexual acts with study partner in last montha4.0 (2.0–10.0)4.0 (2.3–10.0)0.763
Current use of condom (% (n/N))64.7 (77/119)63.4 (64/101)0.888
HPV-positive (%(n/N))51.2 (65/127)58.6 (65/111)0.297
HR-HPV-positive (%(n/N))36.2 (46/127)50.5 (56/111)0.036
Multiple HPV infection (%(n/N))64.6 (42/65)78.5 (51/65)0.080
Multiple HR-HPV infection (%(n/N))73.9 (34/46)80.4 (45/56)0.438
HIV-positive (% (n/N))33.9 (43/127)40.5 (45/111)0.346
CD4+ T-cell count if HIV-positive (cells/μl)a348.5 (240.5–479.8)308 (217.0–484.5)0.471
HIV viral load in HIV-positive men (copies/ml)a4.0 log10 (3.1–4.7)4.2 log10 (3.8–4.8)0.376
Circumcised (% (n/N))93.6 (117/125)95.1 (98/103)0.776
Cigarette use (% (n/N))   
 Never smoked15.7(20/127)18.2 (20/110)0.879
 Ex-smoker17.3 (22/127)16.4 (18/110
 Current smoker66.9 (85/127)65.5 (72/110)
  1. Abbreviations: HPV Human papillomavirus, HR-HPV High-risk human papillomavirus, HIV Human immunodeficiency virus, CST Community state type
  2. #p-values are shown for the comparison of HPV-negative and HPV-positive men. Associations of continuous variables (expressed as medians with interquartile ranges (IQRs, at 25th and 75th percentiles)) and categorical variables were computed by Mann-Whitney unpaired and Chi-square/Fisher’s exact tests, respectively. Significant p-values (< 0.05) are shown in bold
  3. aData was not available on the age at sexual debut for three men (three with Corynebacterium-dominated microbiota), lifetime number of sexual partners of four men (one with Corynebacterium-dominated microbiota and three with non-Corynebacterium-dominated microbiota), number of sexual acts with study partner in the last month of six men (three with Corynebacterium-dominated microbiota and three with non-Corynebacterium-dominated microbiota), CD4+ T-cell count of one man (with Corynebacterium-dominated microbiota) and viral load measurement for thirty one men (seven with Corynebacterium-dominated microbiota and twenty four with non-Corynebacterium-dominated microbiota).