Fig. 2

Alpha diversity a Hierarchical clustering curves for different samples and different groups. The curves numbered the OTUs in the sample in order of relative abundance from large to small, and then took the ranking number of OTUs as the abscissa and the relative abundance of OTUs as the ordinate, and connected these points with broken lines. The curves are shown by sample and group analysis, respectively. b Species accumulation boxplot. The abscissa represents the sample size and the ordinate represents the number of OTU after sampling. The results reflect the rate of new OTU under continuous sampling. c Venn graph of OTUs clustering. Venn graph shows the common and unique OTUs between the different groups. A. total common 1030 OTUs were obtained. A total of 75 OTUs was special for breast cancer and 232 OTUs was special for normal group. d Observed and PD-whole-tree indexes box between groups. The two box plots show the median species diversity within the group. Alpha-diversity indice is significantly higher in the (normal) N group patients compared with in the (breast cancer) BC group patients (P < 0.05)