Table 1 Transcription changes in the Δcse mutant
Accession | Gene symbol | Description | Fold change | FDR |
|---|---|---|---|---|
Heterocyst-related genes | ||||
asr0098 | unknown protein | 2.1 | 0.049 | |
alr0099 | hetZ | heterocyst differentiation | 4.1 | 0.018 |
asr0100 | patU5 | heterocyst inhibitor | 3.5 | 5.69E-06 |
alr0101 | patU3 | heterocyst inhibitor | 3.4 | 4.04E-05 |
all0521 | patA | two-component response regulator, heterocyst pattern formation protein | 2.6 | 0.002 |
asr1734 | heterocyst inhibitor | 1.9 | 0.002 | |
asl2301 | patS | heterocyst-inhibiting signalling peptide | 2.7 | 1.82E-06 |
alr2817 | hetC | heterocyst differentiation protein | −1.3 | 0.009 |
alr2818 | hetP | heterocyst differentiation protein | 2.3 | 0.036 |
alr4392 | ntcA | nitrogen-responsive regulatory protein | −1.3 | 0.007 |
alr2822 – alr2841 | hep | Heterocyst Envelope Polysaccharide island | −2.5 | < 0.016 |
alr0267 | hesF | exoprotein for filament adhesion | −4.8 | 3.42E-04 |
all5341 – all5359 | hgl, hgd, het | glycolipid biosynthesis: glycosyltransferases, hgdA-C, hglA-G/T, hetN/I | −4.5 | < 0.034 |
all2512 | patB | heterocyst-specific transcriptional regulator | −4.7 | 0.026 |
all0177 | flv1B | heterocyst-specific flavodiiron protein | −3.7 | 5.19E-09 |
all0178 | flv3B | heterocyst-specific flavodiiron protein | −3.1 | 0.034 |
all1430 | fdxH | heterocyst ferredoxin | −5.5 | 6.44E-07 |
alr2514 | cox2B | cytochrome c oxidase 2 subunit II | −3.9 | 0.003 |
alr2515 | cox2A | cytochrome c oxidase 2 subunit I | −4.0 | 0.003 |
alr2516 | cox2C | cytochrome c oxidase 2 subunit III | −4.4 | 0.032 |
alr2729 | putative membrane protein | −4.3 | 2.70E-09 | |
alr2730 | putative membrane protein | −3.8 | 0.001 | |
alr2731 | cox3B | cytochrome c oxidase 3 subunit II | −4.2 | 2.70E-09 |
alr2732 | cox3A | cytochrome c oxidase 3 subunit I | −5.1 | 1.73E-04 |
alr3710 | devB | heterocyst-specific ABC-transporter, membrane fusion protein | −4.0 | 3.04E-06 |
alr3711 | devC | heterocyst-specific ABC-transporter, membrane spanning subunit | −3.2 | 0.009 |
alr3712 | devA | heterocyst-specific ABC-transporter, ATP-binding subunit | −3.7 | 0.007 |
Nitrogen fixation | ||||
alr1407 | nifV1 | homocitrate synthase | −3.8 | 8.36E-05 |
asr1408 | nifZ | iron-sulfur cofactor synthesis protein | −4.0 | 0.005 |
asr1409 | nifT | nitrogen fixation protein | −3.6 | 0.003 |
all1424 – all1427 | nitroreductase family protein, ankyrin, CBS domain containing membrane protein | −3.1 | < 0.016 | |
all1431 – all1440 | hes & nif | iron-sulfur cluster biosynthesis protein hesA/B, nifW/X/N/E/K | −5.4 | < 0.038 |
all1455 | nifH | nitrogenase iron protein | −6.5 | 4.06E-06 |
all1456 | nifU | nitrogen fixation protein | −4.2 | 0.009 |
all1457 | nifS | nitrogenase cofactor synthesis protein | −6.0 | 0.025 |
all1517 | nifB | nitrogen fixation protein | −6.4 | 7.81E-06 |
alr2520 | nitrogenase-associated protein | −4.6 | 7.18E-05 | |
Hydrogenases | ||||
all0688 – alr0700 | hup | uptake hydrogenase | −2.7 | < 0.009 |
alr0766 | hoxH | bidirectional hydrogenase large subunit | 5.9 | 0.050 |
Chlorophyll + pyrimidine biosynthesis | ||||
all1357 | hemF2 | coproporphyrinogen III oxidase | 17.9 | 0.011 |
alr1358 | Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 1 | 4.2 | 2.73E-04 | |
alr1912 | dihydroorotate dehydrogenase (fumarate) | 6.5 | 0.024 | |
Other gene clusters | ||||
all2126 | −4.0 | 2.06E-07 | ||
all2127 | radical S-adenosyl-L-methionine | −6.2 | 1.52E-04 | |
all2128 | −7.2 | 0.001 | ||
alr2522 – alr2527 | unknown proteins, luciferase-alpha subunit | −4.1 | < 0.005 | |
all7191 – all7223 | AIPR protein, ABC transporter, plasmid recombinant protein, ATPase, restriction endonuclease, integrase/recombinase, similar to TrsK protein, two-component response regulator | 3.2 | < 0.050 | |