Primary progressive multiple sclerosis in a Russian cohort: relationship with gut bacterial diversity

BMC Microbiology

Table 2 Relative abundance (%, median values) of dominant OTUs in human faecal samples collected from the healthy subjects and patients with primary progressive multiple sclerosis (PPMS)

Dominant OTUs		PPMS	Healthy subjects	p-value
1	Faecalibacterium prausnitzii	11.2	11.3	0.35
2	Bifidobacterium sp.	1.8	0.1	0.12
3	unc. Lachnospiraceae ^a	2.5	4.2	0.19
4	Ruminococcus bromii	3.5	2.3	0.22
5	*Gemmiger sp.*	2.2	1.0	0.03^b
6	Collinsella sp.	1.0	0.8	0.47
7	Bacteroides sp.	1.4	0.7	0.71
8	Blautia wexlerae	0.4	1.2	0.10
9	Prevotella copri	1.3	0.0	0.46
10	Eubacterium hallii	1.8	0.8	0.14
11	*unc.Ruminococcaceae*	1.7	0.2	0.00
13	Anaerostipes sp.	1.1	1.8	0.22
16	Blautia luti	0.4	1.4	0.08

^a “unc.” stands for unclassified;
^b the rows with statistically significant (P ≤ 0.05) differences between the cohorts’ medians are highlighted in bold

ISSN: 1471-2180