Table 1 Relative abundance (%, median values) of family-specific 16S rRNA gene amplicon sequences in human faecal samples collected from healthy subjects and patients with primary progressive multiple sclerosis (PPMS)
Family | PPMS | Healthy | p-value |
|---|---|---|---|
Ruminococcaceae | 31.9 | 28.2 | 0.23 |
Lachnospiraceae | 17.1 | 26.5 | 0.06 |
Bacteroidaceae | 2.7 | 1.6 | 0.84 |
Prevotellaceae | 1.8 | 1.0 | 0.74 |
Bifidobacteriaceae | 4.0 | 2.1 | 0.44 |
unc. Clostridiales a | 4.2 | 2.6 | 0.09 |
Coriobacteriaceae | 2.2 | 1.4 | 0.15 |
unc. Firmicutes | 2.3 | 0.3 | 0.01b |
Veillonellaceae | 2.2 | 1.9 | 0.87 |
Acidaminococcaceae | 1.1 | 0.02 | 0.04 |
Porphyromonadaceae | 0.9 | 0.5 | 0.23 |
unc. Clostridia | 0.5 | 0.07 | 0.04 |
Eubacteriaceae | 1.5 | 0.5 | 0.01 |
Rikenellaceae | 0.6 | 0.2 | 0.07 |
Streptococcaceae | 0.3 | 0.6 | 0.59 |
Erysipelotrichaceae | 0.4 | 0.4 | 0.62 |
Verrucomicrobiaceae | 0.09 | 0.00 | 0.01 |
unc. Bacteria | 0.31 | 0.06 | 0.16 |
Peptostreptococcaceae | 0.5 | 0.1 | 0.12 |
Lactobacillaceae | 0.01 | 0.00 | 0.10 |
Methanobacteriaceae | 0.07 | 0.00 | 0.06 |
Clostridiaceae_1 | 0.01 | 0.1 | 0.57 |
Sutterellaceae | 0.09 | 0.06 | 0.93 |
Desulfovibrionaceae | 0.36 | 0.05 | 0.00 |
Enterobacteriaceae | 0.1 | 0.3 | 0.13 |
Actinomycetaceae | 0.03 | 0.01 | 0.01 |
Clostridiales_i.s._XIII | 0.003 | 0.000 | 0.17 |
Oxalobacteraceae | 0.004 | 0.000 | 0.03 |
Christensenellaceae | 0.005 | 0.000 | 0.01 |
Corynebacteriaceae | 0.003 | 0.000 | 0.01 |