Table 1 Counts (colony-forming units, CFU) of five Gram-negative bacteria after co-culturing with different concentrations of CHIR-090
| Â | Bacteria | CFU | |||||
|---|---|---|---|---|---|---|---|
Blank | DMSO | 8 μg/mL | 40 μg/mL | 80 μg/mL | 200 μg/mL | ||
Sensitive | Escherichia coli | > 500 | > 500 | 4 | 0 | 0 | 0 |
Pseudomonas aeruginosa | > 500 | > 500 | 46 | 0 | 0 | 0 | |
Klebsiella pneumoniae | > 500 | > 500 | > 500 | > 500 | 26 | 0 | |
Proteus vulgaris | > 500 | > 500 | 0 | 0 | 0 | 0 | |
Insensitive | Bacteroides vulgatus | > 500 | > 500 | > 500 | > 500 | > 500 | > 500 |