Fig. 2

Cluster of Orthologous groups (COG) categories in B. clausii genomes. The X-axis represents the COG groups and the Y-axis represents the average number of proteins in respective COG groups. The genomes of B. clausii are clustered as per the properties. B. clausii Heroin represents all the organisms isolated from the Heroin samples [PRJNA395369]. B. clausii Probiotics represents all the probiotic strains as a single category. The COG categories are identified by capital letters as follows: A, RNA processing and modification; B, Chromatin structure and dynamics; C, energy production and conversion; D, cell cycle control, cell division and chromosome partitioning; E, amino acid transport and metabolism; F, nucleotide transport and metabolism; G, carbohydrate transport and metabolism; H, coenzyme transport and metabolism; I, lipid transport and metabolism; J, translation; K, transcription; L, replication; M, cell wall/membrane/envelope biogenesis; N, cell motility; O, post-translational modification, protein turnover, chaperones; P, inorganic ion transport and metabolism; Q, secondary metabolites biosynthesis, transport and catabolism; R, general function prediction only; S, function unknown; T, signal transduction mechanisms; U, intracellular trafficking and secretion; V, defense mechanisms; and X, Mobilome: prophages, transposons