Table 2 Differentially expressed genes from RNASeq analysis of M. catarrhalis 195ME ModM3 ON and OFF strains
Locus tag | Annotation | Fold change ON:OFF | Function (Localization) |
|---|---|---|---|
Increased expression in modM3 ON | |||
 RS06580 | Type III DNA methyltransferase ModM3 | 9.03 | Restriction/modification (C) |
 RS06575 | Type III restriction endonuclease Res | 5.49 | Restriction/modification (C) |
 RS08120 | Type I-F CRISPR-associated protein Csy1 | 1.44 | Unknown (C) |
 RS04785 | Nitrate/nitrite response regulator NarL | 1.40 | Transcription regulation (C) |
 RS07320 | YcgN family cysteine cluster protein | 1.39 | Unknown (U) |
 RS08115 | Type I-F CRISPR-associated protein Csy2 | 1.36 | Unknown (C) |
 RS07645 | Copper-containing nitrite reductase AniA | 1.33 | Nitrogen metabolism (OM) |
 RS09480 | Hypothetical protein | 1.33 | Unknown (U) |
 RS07655 | Nitric oxide reductase NorB | 1.32 | Nitrogen metabolism (IM) |
 RS03495 | DNA repair protein RadA | 1.31 | DNA repair (C) |
 RS08110 | Type I-F CRISPR-associated protein Csy3 | 1.31 | Unknown (C) |
 RS09415 | Type-F conjugative transfer system protein TraW | 1.29 | Conjugation (U) |
 RS04780 | Nitrate/nitrite sensor histidine kinase NarX | 1.29 | Signal transduction (IM) |
 RS06570 | L-2,4-diaminobutyrate decarboxylase ddc | 1.27 | Intermediary metabolism (C) |
 RS03200 | AhpC/TSA family peroxiredoxin | 1.27 | Oxidative stress response (C) |
 RS00630 | 2,4-dienoyl-CoA reductase FadH | 1.27 | Fatty acid metabolism (C) |
 RS02150 | Signal transduction protein | 1.27 | Unknown (U) |
Decreased expression in modM3 ON | |||
 RS05055 | NADH-quinone oxidoreductase subunit NuoB | 0.79 | Energy metabolism (IM) |
 RS04595 | Hypothetical protein | 0.78 | Unknown (U) |
 RS03500 | Sulfate ABC transporter ATP-binding protein CysA | 0.78 | Transport and binding proteins (IM) |
 RS04010 | DUF1049 domain-containing protein | 0.77 | Unknown (IM) |
 RS04620 | Hypothetical protein | 0.76 | Unknown (U) |
 RS06595 | 7-carboxy-7-deazaguanine synthase QueE | 0.75 | Nucleotide metabolism (C) |
 RS05010 | NADH-quinone oxidoreductase subunit NuoK | 0.74 | Energy metabolism (IM) |
 RS02815 | Hypothetical Moraxella Phage protein | 0.72 | Prophage functions (U) |
 RS04610 | Hypothetical protein | 0.70 | Unknown (U) |
 RS09365 | Hypothetical protein | 0.66 | Unknown (U) |
 RS06515 | Putative membrane protein | 0.64 | Cell envelope (IM) |
 RS00885 | Hypothetical protein | 0.63 | Unknown (C) |
 RS06750 | Hypothetical protein | 0.63 | Unknown (U) |
 RS05045 | Sulfite exporter TauE/SafE family protein | 0.62 | Anion transport (IM) |