Table 2 Effect of CAMP-A at 5 × MIC and 50 × MIC on the hematological and blood biochemical parameters of the treated mice
Category | Reference | 0.9% NaCl | CAMP-A (5 × MIC) | CAMP-A (50 × MIC) | |
|---|---|---|---|---|---|
Range | Unit | Average ± STDEV | Average ± STDEV | Average ± STDEV | |
Hematology | |||||
 WBC | 0.80–10.60 | 103/μL | 4.93 ± 1.27 | 5.86 ± 0.71 | 5.29 ± 0.78 |
 RBC | 6.50–11.50 | 106/μL | 8.96 ± 0.52 | 8.69 ± 0.31 | 8.74 ± 0.24 |
 HGB | 11.0–16.5 | g/dL | 14.84 ± 0.73 | 14.53 ± 0.25 | 14.50 ± 0.33 |
 HCT | 35.0–55.0 | % | 42.31 ± 2.11 | 41.25 ± 1.07 | 41.32 ± 1.24 |
 MCV | 41.0–55.0 | fL | 47.26 ± 0.49 | 47.53 ± 0.68 | 47.30 ± 0.14 |
 MCH | 13.0–18.0 | pg | 16.59 ± 0.28 | 16.70 ± 0.38 | 16.60 ± 0.13 |
 MCHC | 30.0–36.0 | g/dL | 35.09 ± 0.48 | 35.18 ± 0.53 | 35.15 ± 0.34 |
 Platelet Count | 400–1600 | 103/μL | 754.50 ± 157.60 | 805.75 ± 98.96 | 873.40 ± 62.92 |
 Neutrophil | 0.23–3.60 | 103/μL | 0.72 ± 0.30 | 0.92 ± 0.10 | 0.86 ± 0.28 |
 Lymphocyte | 0.60–8.90 | 103/μL | 3.81 ± 0.96 | 4.35 ± 0.63 | 3.97 ± 0.55 |
 Monocyte | 0.04–1.40 | 103/μL | 0.11 ± 0.05 | 0.20 ± 0.05 | 0.16 ± 0.04 |
 Eosinophil | 0.00–0.51 | 103/μL | 0.26 ± 0.15 | 0.36 ± 0.14 | 0.26 ± 0.06 |
 Basophil | 0.00–0.12 | 103/μL | 0.033 ± 0.020 | 0.038 ± 0.015 | 0.032 ± 0.020 |
 Neutrophil | 6.5–50.0 | % | 14.44% ± 0.06 | 15.73% ± 0.02 | 16.02% ± 0.04 |
 Lymphocyte | 40.0–92.0 | % | 77.61% ± 0.06 | 74.15% ± 0.04 | 75.25% ± 0.03 |
 Monocyte | 0.9–18.0 | % | 2.23% ± 0.01 | 3.35% ± 0.00 | 3.10% ± 0.01 |
 Eosinophil | 0.0–7.5 | % | 4.96% ± 0.02 | 6.13% ± 0.02 | 5.03% ± 0.01 |
 Basophil | 0.0–1.5 | % | 0.76% ± 0.00 | 0.65% ± 0.00 | 0.60% ± 0.00 |
Biochemistry | |||||
 ALT | 27–195 | U/L | 49.000 ± 28.678 | 148.286 ± 99.876 a | 103.200 ± 157.301 b |
 ALB | 2.4–4.3 | g/dL | 3.186 ± 0.069 | 3.043 ± 0.127 | 3.160 ± 0.055 |
 GGT | 0–9 | U/L | < 3 ± 0.000 | < 3 ± 0.000 | < 3 ± 0.000 |