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Table 1 Effect of CAMP-A and CAMP-B at 4 × MIC on the hematological and blood biochemical parameters of the treated mice

From: Antimicrobial efficacy and toxicity of novel CAMPs against P. aeruginosa infection in a murine skin wound infection model

Category

Reference

0.9% NaCl

CAMP-A (4 × MIC)

CAMP-B (4 × MIC)

Range

Unit

Average ± STDEV

Average ± STDEV

Average ± STDEV

Hematology

 WBC

0.80–10.60

103/μL

6.664 ± 1.140

7.174 ± 2.609

6.081 ± 1.161

 RBC

6.50–11.50

106/μL

9.350 ± 0.345

9.503 ± 0.416

8.979 ± 1.026

 HGB

11.0–16.5

g/dL

13.980 ± 0.349

14.271 ± 0.531

14.029 ± 1.005

 HCT

35.0–55.0

%

44.200 ± 1.643

45.143 ± 1.952

43.143 ± 3.132

 MCV

41.0–55.0

fL

47.200 ± 0.837

47.286 ± 0.756

48.286 ± 2.984

 MCH

13.0–18.0

pg

15.000 ± 0.485

15.043 ± 0.282

15.729 ± 0.921

 MCHC

30.0–36.0

g/dL

31.840 ± 1.163

31.700 ± 0.678

32.571 ± 0.854

 Platelet Count

400–1600

103/μL

1021.400 ± 155.307

937.714 ± 251.844

965.714 ± 122.545

 Neutrophil

0.23–3.60

103/μL

1.618 ± 0.437

1.433 ± 0.708

1.380 ± 0.621

 Lymphocyte

0.60–8.90

103/μL

4.568 ± 1.133

5.042 ± 2.140

4.041 ± 0.805

 Monocyte

0.04–1.40

103/μL

0.220 ± 0.189

0.191 ± 0.087

0.244 ± 0.168

 Eosinophil

0.00–0.51

103/μL

0.220 ± 0.068

0.459 ± 0.421

0.373 ± 0.22

 Basophil

0.00–0.12

103/μL

0.038 ± 0.019

0.063 ± 0.059

0.030 ± 0.017

 Neutrophil

6.5–50.0

%

24.60% ± 0.08

21.71% ± 0.11

22.71% ± 0.10

 Lymphocyte

40.0–92.0

%

68.00% ± 0.07

69.29% ± 0.09

66.71% ± 0.07

 Monocyte

0.9–18.0

%

3.20% ± 0.03

2.71% ± 0.01

3.86% ± 0.02

 Eosinophil

0.0–7.5

%

3.40% ± 0.01

5.57% ± 0.03

6.00% ± 0.03

 Basophil

0.0–1.5

%

0.72% ± 0.004

0.73% ± 0.004

0.67% ± 0.004

Biochemistry

 ALT

27–195

U/L

46.400 ± 41.150

27.167 ± 8.704

75.500 ± 45.713

 ALB

2.4–4.3

g/dL

2.960 ± 0.114

2.929 ± 0.160

2.840 ± 0.152

 GGT

0–9

U/L

< 3 ± 0.000

< 3 ± 0.000

< 3 ± 0.000

  1. WBC white blood cells, RBC red blood cells, HGB hemoglobin, HCT hematocrit, MCV mean cell volume, MCH mean cell hemoglobin, MCHC mean cell hemoglobin, ALT alanine transferase, ALB albumin, GGT gamma-glutamyltransferase