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Fig. 4 | BMC Microbiology

Fig. 4

From: Antimicrobial efficacy and toxicity of novel CAMPs against P. aeruginosa infection in a murine skin wound infection model

Fig. 4

Efficacy of CAMPs at 2 × MIC in the clearance of wound bacterial infection and prevention of hepatic dissemination. The skin wound was inoculated with 2.5 × 106 CFU of P. aeruginosa and treated daily with CAMP-A, CAMP-B, polysporin, or 0.9% NaCl. Bacterial counts (log10 CFU/g) were analyzed on day 1, day 3, and day 5. Data are presented as means ± SD (n = 6). a Skin bacterial burden. Different lowercase letters (a, b, c, and d) above bars show significant differences among treatment groups (One-way ANOVA followed by Duncan’s test; p < 0.05). Each letter represents a level of significant difference. b Liver bacterial burden. A lowercase letter (a) above bars indicates a significant difference between NaCl group and other treatment groups (One-way ANOVA followed by Duncan’s test; p < 0.05)

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