Fig. 3

Toxic effect of CAMPs on the histology of the wounded skin. The wounds were treated daily with CAMP-A, CAMP-B and 0.9% NaCl. On day 7, wounded skin tissues were excised and fixed in 10% of formalin, embedded in paraffin, sectioned at 5-μm thickness, and stained with hematoxylin and eosin (H&E). a 0.9% NaCl, (b) 4 × MIC CAMP-A, (c) 4 × MIC CAMP-B, and (d) Skin prior to wound creation. Bar = 100 μm. Representative areas (rectangle) are shown as enlarged images. e Scores of the inflammatory responses in the three treatment groups. The inflammatory infiltration consisted of lymphocytes, macrophages, and neutrophils. Letters indicate the following cell types: e, epidermis; d, dermis; n, neutrophils. Data are presented as means ± SD (n = 6)