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Table 2 Differential abundance of anaerobic bacteria in DA-DTT versus DA-U

From: Optimizing microbiome sequencing for small intestinal aspirates: validation of novel techniques through the REIMAGINE study

 

DA-DTT (n = 43) vs. DA-U (n = 112)

Taxonomy

Average Relative abundance %

DA-DTTa

Average Relative abundance %

DA-Ua

Fold Change (calculated from the GLM)b

P-value

FDR P-value

p_Firmicutes, c_Clostridia, f_Clostridiaceae, g_Clostridium

0.032

0.024

4.06

1.22E-6

4.38E-6

p_Firmicutes, c_Bacilli, f_Enterococcaceae, g_Enterococcus

0.661

0.009

42.18

5.57E-9

2.57E-8

p_Fusobacteria, c_Fusobacteriia, f_Fusobacteriaceae, g_Fusobacterium

3.625

2.471

2.29

0.01

0.02

p_Bacteroidetes, c_Bacteroidia, f_Bacteroidaceae, g_Bacteroides

0.626

0.073

28.08

1.08E-9

5.43E-9

  1. P-value< 0.05 and FDR P-value< 0.05 are shown in bold. aThe relative abundances were calculated from the original counts (number of sequences in the OTU table). bFold changes were calculated from the GLM, which corrects for differences in library size between the samples and the effects of confounding factors. It is therefore not possible to derive these fold changes from the original counts (number of sequences in the OTU table) by simple algebraic calculations