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Table 1 Patient information and clinical features of the CR-hvKP isolates

From: Isolation and characterization of a sequence type 25 carbapenem-resistant hypervirulent Klebsiella pneumoniae from the mid-south region of China

Strain Number Patient Number Age-range Department Collection Date Source Outcome Resistance Determinants Genes PFGE type MLST
CS1 P2 21–30 ICU 2016/12/27 csf Death blaKPC-2, blaSHV-1, blaTEM-1, blaCTX-M-3 A 25
CS11 P1a 41–50 ICU 2016/11/28 sp Survived blaKPC-2, blaSHV-1, blaTEM-1, blaCTX-M-3 A 25
CS12 P1 41–50 ICU 2016/12/6 sp Survived blaKPC-2, blaSHV-1, blaTEM-1, blaCTX-M-3 A 25
CS15 P3a 51–60 IMD 2016/12/21 sp Survived blaKPC-2, blaSHV-1, blaTEM-1, blaCTX-M-3 A 25
CS17 P4 71–80 ICU 2016/12/3 sp Giving up Treatmentb blaKPC-2, blaSHV-1, blaTEM-1, blaCTX-M-3 A 25
CS45 P5 41–50 ICU 2016/11/15 sp Giving up treatment blaKPC-2, blaTEM-1, blaCTX-M-3 A 25
CS47 P6 71–80 ICU 2016/12/28 blood Giving up treatment blaKPC-2, blaTEM-1, blaCTX-M-3 A 25
CS48 P3 51–60 IMD 2016/12/31 sp Survived blaKPC-2, blaSHV-1, blaTEM-1, blaCTX-M-3 A 25
CS57 P3 51–60 IMD 2017/3/11 sp Survived blaKPC-2, blaSHV-1, blaTEM-1, blaCTX-M-3 A 25
CS60 P14 61–70 CSD 2017/6/16 puncture fluid Giving up treatment bla SHV-1 H 25
CS61 P15 31–40 ICU 2017/6/4 drainage liquid Death bla SHV-1 H 25
CS62 P8 51–60 ICU 2017/6/16 sp Survived bla SHV-1 C 25
CS70 P1 41–50 RD 2017/6/22 sp Survived blaTEM-1, blaCTX-M-3 A 25
CS80 P13 61–70 Burn Unit 2017/7/2 traumatic secretion Death blaKPC-2, blaSHV-1, blaTEM-1, blaCTX-M-65 G 11
CS90 P9 51–60 Outpatient 2017/3/27 drainage liquid Survived blaSHV-1, blaCTX-M-65 D 375
CS103 P11 41–50 ICU 2017/5/22 sp Giving up treatment blaKPC-2, blaSHV-1 F 11
CS118 P12 71–80 ICU 2017/3/18 sp Giving up treatment blaKPC-2, blaSHV-1, blaTEM-1, blaCTX-M-65 F 11
CS127 P10 41–50 Outpatient 2017/5/11 blood Survived bla SHV-1 E 25
CS129 P1 41–50 ICU 2017/3/16 sp Survived blaKPC-2, blaSHV-1, blaCTX-M-3 A 25
CS59497 P7 51–60 ICU 2014/10/5 sp Survived blaNDM-1, blaSHV-1, blaTEM-1 B 25
  1. Department: indicates the department at the Xiangya Hospital, where the samples were collected; ICU Intensive care unitm, IMD Integrative Medicine Department, CSD Cerebrovascular Surgery Department, RD Rehabilitation Department, mCIM Modified Carbapenem Inactivation Method, PFGE Pulsed Field Gel Electrophoresis, MLST Multilocus sequence type
  2. CSF” Cerebrospinal fluid, “Sp” Sputum
  3. aPatients P1 and P3 are immunocompromised patients. Repeated infections occurred in these two patients during 2016 and 2017
  4. bThe patient’s condition deteriorated so the patient stopped any further treatment