Antibiotic | Cell Wall Active | Mechanism of Action |
---|---|---|
Vancomycin (VAN) | + | interferes with cell wall synthesis by preventing formation and crosslinking of peptidoglycan strands [26,27,28] |
Piperacillin (PIP) | + | interferes with cell wall synthesis by binding to enzymes required for the extracytoplasmatic stage of cell wall formation [28, 29] |
Ciprofloxacin (CIP) | – | prevents replication of bacterial DNA by inhibiting DNA gyrase [30, 31] |
Clindamycin (CLI) | – | inhibits bacterial protein synthesis by binding to 50S ribosomal subunits [32] |