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Table 2 Effect of L. plantarum C88 on the levels of IL-1β, IL-6, IL-8, IL-10, IFN-γ, and TNF-α in serum

From: Lactobacillus plantarum C88 protects against aflatoxin B1-induced liver injury in mice via inhibition of NF-κB–mediated inflammatory responses and excessive apoptosis

Group

IL-1β (pg/ml)

IL-6 (pg/ml)

IL-8 (pg/ml)

IL-10 (ng/ml)

IFN-γ (pg/ml)

TNF-α (pg/ml)

Control

43.45 ± 3.90 c

67.24 ± 8.35 c

110.26 ± 15.02 c

161.79 ± 9.93 a

163.24 ± 17.90 b

208.85 ± 33.03 c

AFB1

99.23 ± 5.52 a

123.56 ± 12.73 a

143.40 ± 11.80 a

153.28 ± 10.90 a

252.55 ± 19.65 a

313.53 ± 44.17 a

Viable C88

41.52 ± 4.34 c

74.83 ± 8.49 c

91.77 ± 15.58 d

168.72 ± 8.46 a

169.68 ± 17.81 b

204.39 ± 31.40 c

Heated-killed C88

42.49 ± 4.21 c

72.35 ± 9.83 c

98.41 ± 6.83 d

166.97 ± 10.49 a

166.88 ± 16.29 b

208.37 ± 29.18 c

AFB1 + Viable C88

68.82 ± 3.72 b

109.24 ± 13.51 b

128.11 ± 13.21 b

155.80 ± 7.28 a

236.83 ± 20.53 a

269.04 ± 24.65 b

AFB1 + Heated-killed C88

79.25 ± 4.56 b

113.52 ± 11.69 b

130.29 ± 11.77 b

153.29 ± 9.84 a

241.01 ± 21.88 a

278.23 ± 33.42 b

  1. The results are expressed as mean ± S.D.; each data point is the average of 3 repeated measurements from 10 independently replicated experiments (n = 10)
  2. The different letters in the same rows mean significant difference (P < 0.05), the same letters in the same rows mean insignificant difference (P > 0.05)