Fig. 2

Venn diagrams indicating the number of surface-exposed orthologous proteins shared between Candida species. C. glabrata, C. parapsilosis and C. tropicalis cells were cultured for 16 or 72 h at 37 °C and then cell surface shaved with trypsin to identify surface-exposed proteins via LC-MS/MS. The functions of the identified proteins were assigned on the basis of GO annotations from the CGD and SGD. The numbers of shared or exclusive orthologous proteins identified in C. glabrata, C. parapsilosis and C. tropicalis were compared according to the two major groups of proteins identified under all tested growth conditions i.e. a, typical cell wall proteins, stress response proteins, ribosomal and nuclear proteins and proteins with unknown function; and b, moonlighting proteins, that are metabolic enzymes primarily involved in essential intracellular metabolic processes