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Table 1 The Characteristic of antibiotic resistance of H. pylori isolates in Zhuanghe

From: The antibiotic resistance of Helicobacter pylori to five antibiotics and influencing factors in an area of China with a high risk of gastric cancer

Characteristic N MNZ CAM LVX AMX TCN
OR(95%CI) P value OR(95%CI) P value OR(95%CI) P value OR(95%CI) P value OR(95%CI) P value
Age
 ≤ 60 vs > 60 17 vs 83 0.420 (0.088–1.996) 0.275 0.581 (0.198–1.705) 0.323 1.160 (0.407–3.305) 0.780 1.778 (0.207–15.236) 0.6 0.824 (0.205–3.306) 0.784
Gender
 Female vs male 46 vs 54 1.553 (0.600–4.020) 0.364 4.457 (1.694–11.724) 0.002 1.571 (0.709–3.483) 0.266 1.745 (0.410–7.422) 0.451 2.619 (0.770–8.903) 0.123
Clinical outcome
 GEU vs NGEU 32 vs 63 1.006 (0.318–3.182) 0.992 0.857 (0.325–2.261) 0.756 0.613 (0.242–1.553) 0.302 1.180 (0.252–5.537) 0.834 1.886 (0.504–7.056) 0.346
 GA vs GS 36 vs 20 4.356 (0.854–22.223) 0.077 0.258 (0.058–1.138) 0.073 0.608 (0.202–1.832) 0.377 0.301 (0.032–2.808) 0.292 1.567 (0.342–7.180) 0.563
 GEU vs GS 32 vs 20 1.683 (0.496–5.709) 0.403 0.632 (0.201–1.982) 0.431 1.694 (0.586–4.898) 0.33 0.534 (0.101–2.816) 0.46 0.74 (0.162–3.417) 0.704
 GEU vs GA 32 vs 36 0.463 (0.063–3.395) 0.449 3.182 (0.563–17.972) 0.19 2.197 (0.628–7.691) 0.218 0.966 (0.074–12.669) 0.979 0.214 (0.034–1.368) 0.103
Year
 1998 to 2017 100 1.276 (0.638–2.551) 0.491 1.543 (0.823–2.892) 0.176 2.089 (1.142–3.821) 0.017 5.035 (1.327–19.105) 0.018 1.161 (0.540–2.499) 0.702
Virulence factors
 cagA- vs cagA+ 13 vs 87 1.509 (0.409–5.561) 0.537 2.192 (0.427–11.235) 0.347 5.133 (1.297–20.319) 0.02 0 0.999 0 0.999
 babA2- vs babA2+ 18 vs 82 1.374 (0.423–4.456) 0.597 0.822 (0.257–2.627) 0.741 0.789 (0.276–2.303) 0.676 0.854 (0.158–4.634) 0.855 1.606 (0.316–8.159) 0.568
 hrgA- vs hrgA+ 43 vs 57 0.518 (0.188–1.431) 0.205 0.419 (0.166–1.059) 0.066 0.708 (0.315–1.591) 0.403 1.839 (0.458–7.385) 0.391 1.749 (0.569–5.376) 0.329
 slyD- vs slyD+ 54 vs 46 0.519 (0.196–1.376) 0.187 0.585 (0.233–1.470) 0.254 0.334 (0.146–0.764) 0.009 0.144 (0.017–1.205) 0.074 0.883 (0.282–2.765) 0.831
 opiA- vs opiA+ 33 vs 67 0.435 (0.141–1.340) 0.147 1.163 (0.424–3.193) 0.769 0.501 (0.203–1.236) 0.133 0.404 (0.100–1.632) 0.203 0.557 (0.179–1.731) 0.312
 vacAi1- vs vacAi1+ 36 vs 64 0.490 (0.161–1.494) 0.21 0.448 (0.174–1.154) 0.096 0.891 (0.380–2.092) 0.791 0.427 (0.106–1.720) 0.231 0.589 (0.190–1.824) 0.359
 vacAs1m1m2 vs vacAs1m1/m2 42 vs 40 0.287 (0.096–0.863) 0.026 0.763 (0.287–2.027) 0.588 0.749 (0.311–1.804) 0.52 0.434 (0.078–2.420) 0.341 0.758 (0.215–2.667) 0.666
 iceA-- vs iceA−+ 18 vs 21 0.505 (0.071–3.612) 0.496 1.476 (0.369–5.902) 0.582 0.572 (0.135–2.415) 0.447 0.489 (0.090–2.649) 0.406 1.096 (0.222–5.418) 0.91
 iceA-- vs iceA++ 18 vs 61 0.317 (0.065–1.557) 0.157 0.310 (0.094–1.020) 0.054 0.428 (0.134–1.367) 0.152 0.051 (0.005–0.481) 0.009 0.450 (0.106–1.900) 0.277
 iceA− + vs iceA++ 21 vs 61 0.474 (0.122–1.847) 0.282 0.234 (0.071–0.775) 0.017 0.812 (0.294–2.240) 0.688 0.101 (0.009–1.086) 0.059 0.388 (0.099–1.527) 0.176