Unveiling the partners of the DRBD2-mRNP complex, an RBP in Trypanosoma cruzi and ortholog to the yeast SR-protein Gbp2

Table 2 Highlighted enriched proteins in the DRBD2-mRNP complex. Enriched proteins identified in TAP-tagged DRBD2 and control IP assays with differential abundance. TriTrypDB ID and protein description: TriTryp database identification number and description for a given protein; Signal control and Signal DRBD2: PatternLab’s Normalized Ion Abundance Factors (NIAF) from control and DRBD2 replicates; Proteins with fold change > 2 were considered; Product: a given name for the corresponding protein

TriTrypDB ID	Signal control	Signal DRBD2	Fold change	Protein description from TriTrypDB	Product
Tc00.1047053508461.140	2,82E-05	0,004717835	167,14	Poly(A)-binding protein, putative	PABP2
Tc00.1047053510679.40	4,83E-05	0,001303308	26,99	Uncharacterized protein
Tc00.1047053506959.30	8,23E-05	0,001759715	21,38	ATP-dependent DEAD/H RNA helicase	DHH1
Tc00.1047053511635.20	0,00046701	0,005277732	11,3	Histone H2B
Tc00.1047053510769.49	0,000161566	0,001579402	9,78	40S ribosomal protein S6
Tc00.1047053509247.30	6,94E-06	5,86E-05	8,44	Uncharacterized protein
Tc00.1047053508177.90	8,26E-06	6,50E-05	7,87	Uncharacterized protein
Tc00.1047053507831.60	4,00E-05	0,000298381	7,46	Heat shock protein, putative
Tc00.1047053509695.170	0,00046333	0,002714777	5,86	60S ribosomal protein L9, putative
Tc00.1047053510119.20	0,00297696	0,017012608	5,71	Elongation factor 1-alpha	EF1-alfa
Tc00.1047053510963.90	0,00285562	0,011081836	3,88	Elongation factor 2, putative	EF-2
Tc00.1047053510155.180	0,001556005	0,004652216	2,99	Eukaryotic initiation factor 4a	eIF4A

ISSN: 1471-2180