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Table 3 Virulence genotypes of studied isolates

From: Clonal diversity, virulence genes content and subclone status of Escherichia coli sequence type 131: comparative analysis of E. coli ST131 and non-ST131 isolates from Iran

ST131 (n = 69) Non-ST131 (n = 84)
Adhesions O25b-ST131 n = 63 O16-ST131 n = 6 Total ST131 Human (n = 56) Broiler (n = 28) P value
ST131 vs. non-ST131 ST131 vs avian
Virulence markers, n (%)
papA 27 (42.8) 1 (16.7) 28 (40.6) 10 (17.9) 4 (14.3) 0.007 0.01
F10 papA 61 (96.8) 6 (100) 67 (97.1) 17 (30.4) 0 0.001 0.001
papEF 26 (41.3) 1 (16.7) 27 (39.1) 7 (12.5) 3 (10.7) 0.001 0.007
papC 30 (47.6) 1 (16.7) 31 (44.9) 14 (25) 9 (32.1) 0.02
sfa/focDE 1 (1.6) 0 1 (1.4) 1 (1.8) 0
afaFM955459 5 (7.9) 1 (16.7) 6 (8.7) 0 0 0.03
afa/draBC 7 (11.1) 3 (50) 10 (14.5) 5 (8.9) 1 (3.6)
fimH30 62 (98.4) 0 62 (89.9) 27 (48.2) 17 (60.7) 0.001 0.003
Siderophores
fyuA 63 (100) 6 (100) 69 (100) 44 (78.6) 7 (25) 0.001 0.001
iroN 1 (1.6) 0 1 (1.4) 0 17 (60.7) 0.001*
iutA 62 (98.4) 5 (83.3) 67 (97.1) 39 (69.6) 23 (82.1) 0.001 0.02
chuA 62 (98.4) 6 (100) 68 (98.6) 35 (62.5) 12 (43) 0.001 0.001
Toxins
cnf1 18 (28.6) 0 18 (26.1) 2 (3.6) 0 0.001 0.001
sat 62 (98.4) 5 (83.3) 67 (97.1) 18 (32.1) 1 (3.6) 0.001 0.001
hlyA 20 (31.7) 0 20 (29) 4 (7.1) 0 0.003 0.001
hlyF 1 (1.5) 0 1 (1.4) 6 (10.7) 19 (67.9) 0.04 0.001*
Capsules
kpsM T II-K5 34 (54) 0 34 (49.3) 10 (17.9) 13 (46.4) 0.001
kpsMT II-K2 32 (50.8) 2 (33.3) 34 (49.3) 20 (35.7) 20 (71.4) 0.04*
Miscellaneous
ibeA 0 1 (16.7) 1 (1.4) 1 (1.8) 5 (17.9) 0.007*
PAI (malX) 61 (96.8) 5 (83.3) 66 (95.7) 32 (56.1) 5 (17.9) 0.001 0.001
usp 62 (98.4) 6 (100) 68 (98.6) 10 (17.9) 6 (21.4) 0.001 0.001
Protections
traT 60 (95.2) 6 (100) 66 (95.7) 43 (76.8) 20 (71.4) 0.002 0.002
ompT 1 (1.5) 0 1 (1.4) 6 (10.7) 19 (67.9) 0.04 0.001*
iss 1 (1.5) 0 1 (1.4) 7 (12.5) 18 (64.3) 0.02 0.001*
Virulence score (median) 11 8.50 11 6 8 0.001 0.001
Strains with ≥8 virulence genes 62 (98.4) 6 (100) 68 (98.6) 20 (35.7) 16 (57.1) 0.001 0.001
ExPEC status 62 (98.4) 4 (66.7) 66 (95.6) 24 (42.9) 21 (75) 0.001 0.006
  1. *: indicate the positive association with broiler isolates