ST131 (n = 69) | Non-ST131 (n = 84) | ||||||
---|---|---|---|---|---|---|---|
Adhesions | O25b-ST131 n = 63 | O16-ST131 n = 6 | Total ST131 | Human (n = 56) | Broiler (n = 28) | P value | |
ST131 vs. non-ST131 | ST131 vs avian | ||||||
Virulence markers, n (%) | |||||||
 papA | 27 (42.8) | 1 (16.7) | 28 (40.6) | 10 (17.9) | 4 (14.3) | 0.007 | 0.01 |
 F10 papA | 61 (96.8) | 6 (100) | 67 (97.1) | 17 (30.4) | 0 | 0.001 | 0.001 |
 papEF | 26 (41.3) | 1 (16.7) | 27 (39.1) | 7 (12.5) | 3 (10.7) | 0.001 | 0.007 |
 papC | 30 (47.6) | 1 (16.7) | 31 (44.9) | 14 (25) | 9 (32.1) | 0.02 | – |
 sfa/focDE | 1 (1.6) | 0 | 1 (1.4) | 1 (1.8) | 0 | – | – |
 afaFM955459 | 5 (7.9) | 1 (16.7) | 6 (8.7) | 0 | 0 | 0.03 | – |
 afa/draBC | 7 (11.1) | 3 (50) | 10 (14.5) | 5 (8.9) | 1 (3.6) | – | – |
 fimH30 | 62 (98.4) | 0 | 62 (89.9) | 27 (48.2) | 17 (60.7) | 0.001 | 0.003 |
Siderophores | |||||||
 fyuA | 63 (100) | 6 (100) | 69 (100) | 44 (78.6) | 7 (25) | 0.001 | 0.001 |
 iroN | 1 (1.6) | 0 | 1 (1.4) | 0 | 17 (60.7) | – | 0.001* |
 iutA | 62 (98.4) | 5 (83.3) | 67 (97.1) | 39 (69.6) | 23 (82.1) | 0.001 | 0.02 |
 chuA | 62 (98.4) | 6 (100) | 68 (98.6) | 35 (62.5) | 12 (43) | 0.001 | 0.001 |
Toxins | |||||||
 cnf1 | 18 (28.6) | 0 | 18 (26.1) | 2 (3.6) | 0 | 0.001 | 0.001 |
 sat | 62 (98.4) | 5 (83.3) | 67 (97.1) | 18 (32.1) | 1 (3.6) | 0.001 | 0.001 |
 hlyA | 20 (31.7) | 0 | 20 (29) | 4 (7.1) | 0 | 0.003 | 0.001 |
 hlyF | 1 (1.5) | 0 | 1 (1.4) | 6 (10.7) | 19 (67.9) | 0.04 | 0.001* |
Capsules | |||||||
 kpsM T II-K5 | 34 (54) | 0 | 34 (49.3) | 10 (17.9) | 13 (46.4) | 0.001 | – |
 kpsMT II-K2 | 32 (50.8) | 2 (33.3) | 34 (49.3) | 20 (35.7) | 20 (71.4) | – | 0.04* |
Miscellaneous | |||||||
 ibeA | 0 | 1 (16.7) | 1 (1.4) | 1 (1.8) | 5 (17.9) | – | 0.007* |
 PAI (malX) | 61 (96.8) | 5 (83.3) | 66 (95.7) | 32 (56.1) | 5 (17.9) | 0.001 | 0.001 |
 usp | 62 (98.4) | 6 (100) | 68 (98.6) | 10 (17.9) | 6 (21.4) | 0.001 | 0.001 |
Protections | |||||||
 traT | 60 (95.2) | 6 (100) | 66 (95.7) | 43 (76.8) | 20 (71.4) | 0.002 | 0.002 |
 ompT | 1 (1.5) | 0 | 1 (1.4) | 6 (10.7) | 19 (67.9) | 0.04 | 0.001* |
 iss | 1 (1.5) | 0 | 1 (1.4) | 7 (12.5) | 18 (64.3) | 0.02 | 0.001* |
Virulence score (median) | 11 | 8.50 | 11 | 6 | 8 | 0.001 | 0.001 |
Strains with ≥8 virulence genes | 62 (98.4) | 6 (100) | 68 (98.6) | 20 (35.7) | 16 (57.1) | 0.001 | 0.001 |
ExPEC status | 62 (98.4) | 4 (66.7) | 66 (95.6) | 24 (42.9) | 21 (75) | 0.001 | 0.006 |