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Table 1 The host range and EOP for UPMK_1 and UPMK_2

From: Genomic analyses of two novel biofilm-degrading methicillin-resistant Staphylococcus aureus phages

Indicator host

UPMK_1/MRSAt127/4a

UPMK_2/MRSAt223/20a

Spot test

Titer PFU/mL

EOP

Spot test

Titer PFU/mL

EOP

MRSA t127/1

I

1 × 104

1 × 10−6

I

1 × 105

1 × 10−5

MRSA t127/2

I

1 × 105

1 × 10−5

S

1 × 106

1 × 10−4

MRSA t127/3

S

1 × 109

0.1

S

1 × 1010

1

MRSA t127/4

Phage production host

 

S

1 × 1010

1

MRSA t127/5

S

1 × 108

1 × 10−2

S

1 × 107

1 × 10−3

MRSA t127/6

R

–

–

R

–

–

MRSA t127/7

R

–

–

R

–

–

MRSA t127/8

I

1 × 104

1 × 10−6

S

1 × 106

1 × 10−4

MRSA t2246/9

I

1 × 104

1 × 10−6

I

1 × 105

1 × 10−5

MRSA t127/10

I

1 × 104

1 × 10−6

S

1 × 106

1 × 10−4

MRSA t127/11

R

–

–

I

1 × 105

1 × 10−5

MRSA t127/12

S

1 × 106

1 × 10−4

S

1 × 107

1 × 10−3

MRSA t127/13

I

1 × 104

1 × 10−6

S

1 × 106

1 × 10−4

MRSA t127/14

S

1 × 106

1 × 10−4

S

1 × 107

1 × 10−3

MRSA t127/15

I

1 × 104

1 × 10−6

S

1 × 107

1 × 10−3

MRSA t127/16

S

6 × 107

1 × 10−3

S

1 × 107

1 × 10−3

MRSA t127/17

S

1 × 106

1 × 10−4

S

1 × 106

1 × 10−4

MRSA t127/18

S

1 × 107

1 × 10−3

S

1 × 1010

1

MRSA t790/19

R

–

–

I

1 × 102

1 × 10−8

MRSA t223/20

R

–

–

Phage production host

 

MRSA t127/21

I

1 × 104

1 × 10−6

S

1 × 107

1 × 10−3

MRSA t127/22

I

1 × 104

1 × 10−6

S

1 × 106

1 × 10−4

MRSA t127/23

S

1 × 106

1 × 10− 4

S

1 × 107

1 × 10−3

MRSAt127/24

I

1 × 104

1 × 10−6

I

1 × 105

1 × 10−5

MRSAt127/25

I

1 × 104

1 × 10−6

S

1 × 106

1 × 10−4

  1. a Phage production host used; MRSA t127 represents spa type 127, MRSA t223 represents spa type 223
  2. A titer of 1 × 1010 PFU/mL for UPMK_1 and UPMK_2 was used in both spot test and EOP
  3. The host range and susceptibility of the bacterial isolates were the clear spot (susceptible; S), turbid spot (intermediate; I), and no plaque formation or killing effect detected (resistant; R)
  4. The considered EOP values were EOP > 0.5 for high production, 0.1 < EOP < 0.5 for medium production, 0.001 < EOP < 0.1 for low production, and EOP < 0.001 for very low production
  5. The data were presented as the mean of triplicate independent measurements