Table 2 Determination of eleven antibiotics MICs of overexpression strains carrying different rpoB point mutations
From: Rifampin resistance and its fitness cost in Riemerella anatipestifer
Strain | Rifampin (μg/mL) | Ampicillin (μg/mL) | Cefuroxime (μg/mL) | Erythromycin (μg/mL) | Aztreonam (μg/mL) | Ciprofloxacin (μg/mL) | Kanamycin (μg/mL) | Chloramphenicol (μg/mL) | Clindamycin (μg/mL) | Sulfamethoxazole (μg/mL) | Vancomycin (μg/mL) |
|---|---|---|---|---|---|---|---|---|---|---|---|
ATCC11845 | < 0.25 | < 0.25 | 0.5 | < 0.25 | 4 | < 0.25 | 128 | 4 | < 0.25 | 256 | 32 |
ATCC11845-pLMF03 | < 0.25 | 128 | > 256 | < 0.25 | 4 | < 0.25 | 256 | 4 | < 0.25 | 256 | 32 |
ATCC11845-pLMF03::rpoB | < 0.25 | 128 | 256 | < 0.25 | 4 | < 0.25 | 128 | 4 | < 0.25 | 256 | 32 |
ATCC11845-pLMF03::rpoB(V382I) | 256 | 32 | 128 | 8 | 4 | 4 | 256 | 16 | 0.5 | 256 | 32 |
ATCC11845-pLMF03::rpoB(H491N) | 128 | 64 | 256 | 8 | 8 | 8 | 256 | 32 | 1 | 256 | 32 |
ATCC11845-pLMF03::rpoB(R494K) | 128 | 128 | > 256 | 8 | 8 | 8 | 256 | 32 | 1 | 256 | 32 |
ATCC11845-pLMF03::rpoB(G502K) | 128 | 128 | > 256 | 8 | 8 | 8 | 256 | 32 | 1 | 256 | 32 |
ATCC11845-pLMF03::rpoB(S539Y) | 128 | 64 | 256 | 8 | 8 | 8 | 256 | 32 | 1 | 256 | 32 |