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Fig. 6 | BMC Microbiology

Fig. 6

From: Ectromelia virus suppresses expression of cathepsins and cystatins in conventional dendritic cells to efficiently execute the replication process

Fig. 6

ECTV decreases antigen processing in cDCs at later stages of infection. Antigen uptake and processing in JAWS II (a) and GM-BM (b) cells at 4, 12 and 24 hpi with ECTV. Control and infected cells were pulsed with DQ-OVA for 60 min. at 4 °C and 37 °C, and analyzed by flow cytometry. Representative histograms show mean fluorescence intensity (MFI) of DQ-OVA green fluorescence at 4 °C and 37 °C in JAWS II and GM-BM cells. Graphs represent individual data of MFI for DQ-OVA green fluorescence at 37 °C from three independent experiments (*p ≤ 0.05, **p ≤ 0.01)

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