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Table 4 Summary of CDSs annotated to antibiotic resistance between SO-1977, MRSA252 and MSSA476 strains

From: Genomic analysis of methicillin-resistant Staphylococcus aureus strain SO-1977 from Sudan

No SO-1977 MRSA252 MSSA476 Seed subsystem Seed function Length (bp) Contig number
1   Peptidoglycan Biosynthesis Methicillin resistance determinant MecA, transpeptidase 2007 Contig 000034
2 Multidrug Resistance, 2-protein version Found in Gram-positive bacteria Multidrug resistance protein [function not yet clear] 648 Contig 000037
3 Multidrug Resistance, 2-protein version Found in Gram-positive bacteria Membrane component of multidrug resistance system 1932 Contig 000037
4 Multidrug Resistance, 2-protein version Found in Gram-positive bacteria TetR family regulatory protein of MDR cluster 555 Contig 000037
5    Tetracycline resistance, ribosome protection type Tetracycline resistance protein TetM 1920 Contig 000042
6    Tetracycline resistance, ribosome protection type Translation elongation factor G 2082 Contig 000014
7 Teicoplanin-resistance in Staphylococcus Teicoplanin resistance associated membrane protein TcaA 1209 Contig 000002
8 Teicoplanin-resistance in Staphylococcus Teicoplanin resistance associated membrane protein TcaB 1383 Contig 000002
9 Teicoplanin-resistance in Staphylococcus Teicoplanin-resistance associated HTH-type transcriptional regulator TcaR 456 Contig 000002
10    Quinolone resistance protein norA none 1167 Contig 000007
11   Bicyclomycin resistance protein TcaB none 1212 Contig 000002
12 Transcriptional regulator, MarR family None 456 Contig 000003
13 Transcriptional regulator, MarR family None 420 Contig 000005
14 Transcriptional regulator, MarR family None 210 Contig 000043
15 Transcriptional regulator, MarR family None 435 Contig 000030
16 Transcriptional regulator, MarR family None 441 Contig 000001
17 Transcriptional regulator,MarR family None 468 Contig 000030
18 Resistance to fluoroquinolones DNA gyrase subunit B 2403 Contig 000010
19 Resistance to fluoroquinolones DNA gyrase subunit A 2661 Contig 000011
20 Resistance to fluoroquinolones Topoisomerase IV subunit B 1998 Contig 000010
21 Resistance to fluoroquinolones Topoisomerase IV subunit A 2403 Contig 000010
22 Beta-lactamase Beta-lactamase 1500 Contig 000002
23 Beta-lactamase Beta-lactamase repressor BlaI 381 Contig 000067
24 Multidrug Resistance Efflux Pumps Acriflavin resistance protein 3168 Contig 000001
25 Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps Multidrug Resistance Efflux Pumps 1356 Contig 000005
26   Methicillin resistance in staphylococci HmrB protein involved in methicillin resistance 1600 NC_002952
27 Methicillin resistance in staphylococci Beta-lactamase repressor BlaI 381 Contig 000067
28 Methicillin resistance in staphylococci FmhA protein of FemAB family 1251 Contig 000002
29     Methicillin resistance in staphylococci LytH protein involved in methicillin resistance 1600 NC_002952
30   Methicillin resistance in staphylococci Methicillin resistance regulatory sensor-transducer MecR1 1600 Contig 000034/ NC_002952
31     Methicillin resistance in staphylococci Methicillin resistance repressor MecI 1600 NC_002952
32     Methicillin resistance in staphylococci Transposase for insertion sequence-like element IS431mec 1296 NC_002952
33     Methicillin resistance in staphylococci UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase 1600 NC_002952
34 Methicillin resistance in staphylococci Beta-lactamase regulatory sensor-transducer BlaR1 1089 Contig 000067