Accessory gene regulator (agr) dysfunction was unusual in Staphylococcus aureus isolated from Chinese children

Table 1 Characteristics of patients for samples

Patient characteristics	Total	Dysfunctional agr (N = 10)	Functional agr (N = 159)	P-value
Male sex, N (%)	162 (60.22)	5 (50.00)	157 (60.62)	0.5253
Age (months), median (IQR^a)	11.9 (1.27–55.14)	33.27 (13.15–108.38)	11.33 (1.17–54.90)	0.0797
Age distribution				0.1581
≤ 28 days	59 (21.93)	0	59 (22.78)
29 days–3 years	137 (50.93)	7 (70.00)	130 (50.19)
4–6 years	28 (10.41)	0	28 (10.81)
7–15 years	45 (16.73)	3 (30.00)	42 (16.22)
Origin, N (%)				0.0102
CA	135 (50.19)	1 (10.00)	134 (51.74)
HA	134 (49.81)	9 (90.00)	125 (48.26)
Disease				0.2900
Invasive infection^b, N (%)	80 (29.74)	1 (10.00)	9 (90.00)
Non-invasive infection^c, N(%)	189 (70.26)	79 (30.50)	180 (69.50)
Vancomycin treatment, N (%)	66 (24.54)	2 (20.00)	64 (24.71)	1.0000
Linezolid treatment, N (%)	45 (16.73)	2 (20.00)	43 (16.60)	0.6758
Hospitalization-Median (IQR)	15 (10–24)	21 (10.25–30.25)	14 (10–23)	0.4000

^aIQR interquartile range
^bSSTI Including skin and soft tissue infection, BSI bloodstream infection, CNSI central nervous system infection, IE infective endocarditis, BJI bone and joint infection, SP severe pneumonia, AI intra-abdominal infection. Details were as follows: SSTI (1 case), AI (1 case), CNSI (1 case), BJI (3 cases), SP (11 cases), BSI (11 cases), BSI + SSTI (16 cases), BSI + AI (1 case), BSI + IE (4), BSI + BJI (6 cases), BSI + CNSI (2 cases), BSI + SP (5 cases), BJI + SSTI (1 case), SP + SSTI (1 case), SP + BJI (1 case), BSI + SSTI+CNSI (1 case), BSI + CNSI+IE (1 case), BSI + SP + CNSI (1 case), BSI + SP + SSTI (3 cases), BSI + BJI + SSTI (7 cases), BSI + BJI + SSTI+CNSI (1 cases), BSI + SP + SSTI+CNSI (1 case)
^cIncluding SSTI (83 cases), pneumonia (103 cases), pneumonia+SSTI (2 cases), urinary system infection (1 case)

ISSN: 1471-2180