Table 4 Mutation sites detected in fusA in two methicillin-resistant Staphylococcus aureus (MRSA), 18 methicillin-resistant S. pseudintermedius (MRSP) and 4 methicillin-sensitive S. pseudintermedius (MSSP) isolates
Amino acid substitution | Nucleotide substitution | No. of isolates | Fusidic acid MIC (mg/L) |
|---|---|---|---|
L461K | TTA - > AAA | 2 (SEUK MRSA) | 384a |
I461K | ATT - > AAA | 1 (NUK MSSP) | >  64 |
V90I / A376V / I461T | GTA - > ATA / GCA - > GTA / ATT - > ACT | 1 (NUK MSSP) | >  64 |
20 (n = 12 FA-R Finland MRSP; n = 1 Finland MRSP, n = 2 NUK MSSP, n = 4 NUK MRSP, n = 1 SEUK MRSP) | 64 |