Genetic resistance determinants to fusidic acid and chlorhexidine in variably susceptible staphylococci from dogs

BMC Microbiology

Table 2 Minimum inhibitory concentrations (MICs) of chlorhexidine determined by agar dilution, and presence of resistance determinants, for canine-derived Staphylococcus pseudintermedius and S. aureus isolates (n = 538) from Finland, the U.S.A., North U.K. (NUK), South-East U.K. (SEUK) and Germany

Country	Bacterial Type	n	Chlorhexidine MIC (mg/L)								MIC₅₀	MIC₉₀
Country	Bacterial Type	n	0.125	0.25	0.5	1	2	4	8	16	mg/L	mg/L
Finland	MRSP	49	0	1	35	12	0	1	0	0	0.5	1
Finland	MSSP	50	0	0	38	12	0	0	0	0	0.5	1
U.S.A.	MRSP	50	0	0	35 n = 2 smr	15 n = 1 smr	0	0	0	0	0.5	1
U.S.A.	MSSP	51	0	0	45 n = 1 smr	4	1	1	0	0	0.5	1
NUK^b	MRSP	49	0	0	0	16	25	8	0	0	2	4
NUK^b	MSSP	50	0	0	0	36	14 n = 1 qacA/B	0	0	0	1	2
SEUK^a	MRSP	47	0	0	0	21	23	2	1	0	2	2
	MSSP	44	0	0	1	22	17	2	2	0	1	2
	MRSA	50	0	0	0	0	0	49	1	0	4	4
	MSSA	50	0	0	1	22	22	5 n = 1 qacA/B n = 1 smr	0	0	2	2
Germany^a	MRSP	24	0	0	9	4	11	0	0	0	1	2
Germany^a	MSSP	24	0	0	11	13	0	0	0	0	1	1

MRSP methicillin-resistant Staphylococcus pseudintermedius, MSSP methicillin-sensitive S. pseudintermedius, NUK North U.K., SEUK South-East U.K, MRSA methicillin-resistant S. aureus, MSSA methicillin-susceptible S. aureus.
^aMICs determined as part of previous study by the authors (reference [52])
^bMICs determined as part of previous study by the authors (reference [45])

ISSN: 1471-2180