Table 2 Ciprofloxacin (CIP) and norfloxacin (NOR) susceptibility data for the 22 GC strains with details of GyrA, ParC, MtrR and PorB amino acid substitutions, and mtrR promoter mutation
From: gyrA and parC mutations in fluoroquinolone-resistant Neisseria gonorrhoeae isolates from Kenya
| Isolate ID | MIC(mg/L) | Mutations | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gyr A | Par C | MtrR | A13deletion | PorB | ||||||||
| CIP | NOR | S91 | D95 | E91 | A39 | G45 | H105 | A121 | G120 | N122 | ||
| KNY_NGAMR1 | 0.38 | 1.5 | F | G | ||||||||
| KNY_NGAMR2 | 0.016a | 0.094 | D | A deleted | D | |||||||
| KNY_NGAMR3 | 3 | 6 | F | G | G | T | ||||||
| KNY_NGAMR4 | 0.006a | 0.023 | T | S | K | |||||||
| KNY_NGAMR5 | 4 | 6 | F | G | G | Y | ||||||
| KNY_NGAMR6 | 12 | 12 | F | G | G | T | ||||||
| KNY_NGAMR7 | 8 | 12 | F | G | G | S | K | |||||
| KNY_NGAMR8 | 3 | 6 | F | A | T | |||||||
| KNY_NGAMR9 | 12 | 0.24 | F | A | G | T | ||||||
| KNY_NGAMR10 | 8 | 12 | F | G | G | T | ||||||
| KNY_NGAMR11 | 3 | 8 | F | A | T | |||||||
| KNY_NGAMR13 | 3 | 12 | F | A | T | |||||||
| KNY_NGAMR14 | 16 | 24 | F | G | G | T | S | K | ||||
| KNY_NGAMR15 | 4 | 16 | F | A | T | |||||||
| KNY_NGAMR16 | 8 | 6 | F | G | G | T | ||||||
| KNY_NGAMR17 | 6 | 12 | F | G | G | Y | ||||||
| KNY_NGAMR18 | 0.38 | 0.047 | F | G | G | T | ||||||
| KNY_NGAMR19 | 4 | 8 | F | G | G | T | ||||||
| KNY_NGAMR20 | 8 | 12 | F | A | G | T | ||||||
| KNY_NGAMR21 | 3 | 8 | F | A | T | |||||||
| KNY_NGAMR22 | 4 | 12 | F | G | G | T | ||||||
| KNY_NGAMR23 | 12 | 12 | F | A | G | T | ||||||