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Table 2 Summary of Ambler Class A and C phenotypes and genotypes in ESC-resistant E. coli and K. pneumoniae isolates

From: Epidemiology of paediatric gastrointestinal colonisation by extended spectrum cephalosporin-resistant Escherichia coli and Klebsiella pneumoniae isolates in north-west Cambodia

 

Amber Class Phenotype

E. coli (n = 97)

K. pneumoniae (n = 17)

Both species (n = 114)

Total

A (n = 74)

C (n = 23)

A (n = 14)

C (n = 3)

A (n = 88)

C (n = 26)

(n = 114)

Ambler Class A genes

 blaCTX-M positivea

73 (99%)

18 (78%)

14 (100%)

2 (67%)

87 (99%)

20 (77%)

107 (94%)

  CTX-M-14

14

1

2

0

16

1

17

  CTX-M-15

28

13

12

0

40

13

53

  CTX-M-24

2

1

0

0

2

1

3

  CTX-M-27

12

0

0

2

12

2

14

  CTX-M-55

20

4

0

0

20

4

24

  Total

76

19

14

2

90

21

111

 blaSHV positive

0 (0%)

0 (0%)

12 (86%)

2 (67%)

12 (14%)

2 (8%)

14 (12%)

  SHV-1/1-likec

0

0

2

1

2

1

3

  SHV-11/11-likec

0

0

2

1

2

1

3

  SHV-27b

0

0

1

0

1

0

1

  SHV-28b

0

0

1

0

1

0

1

  SHV-33c

0

0

3

0

3

0

3

  SHV-83c

0

0

1

0

1

0

1

  SHV-99/99-likeb

0

0

1

0

1

0

1

  SHV-142d

0

0

1

0

1

0

1

  Total

0

0

12

2

12

2

14

 blaVEB positive

1 (1%)

0 (0%)

0 (0%)

0 (0%)

1 (1%)

0 (0%)

1 (1%)

 None identified

0

5 (22%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

5 (4%)

Ambler Class C genes

 blaCMY-2 positive

0 (0%)

8 (35%)

0 (0%)

0 (0%)

0 (0%)

8 (31%)

8 (31%)

 blaDHA positive

0 (0%)

1 (4%)

0 (0%)

1 (33%)

0 (0%)

2 (8%)

2 (8%)

 blaACT-like positive

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

0 (0%)

 None identified

0 (0%)

14 (61%)

0 (0%)

2 (67%)

0 (0%)

16 (62%)

16 (62%)

  1. aIsolates with two separate blaCTX-M alleles were identified in 4% of isolates (4/114)
  2. bESBL
  3. cnot ESBL
  4. dUnknown beta-lactamase phenotype