Table 1 Colistin MICs obtained by broth microdilution comparing UMIC Colistine to the reference method (μg/mL). Discrepancies are indicated in bold
From: Comparative evaluation of the UMIC Colistine kit to assess MIC of colistin of gram-negative rods
Bacterial species | Isolates | Samples origins | Genotype | Colistin MIC (μg/mL) | |
|---|---|---|---|---|---|
Reference | UMIC | ||||
Escherichia coli | NCTC 13883 | Human, UK | mcr-1 | 4 | 4 |
SE65 | Human, Algeria | mcr-1 | 4 | 4 | |
117R | Human, Saudi arabia | mcr-1 | 4 | 4 | |
1R2013 | Human, Saudi arabia | mcr-1 | 8 | 8 | |
1R 2104 | Human, Saudi arabia | mcr-1 | 8 | 4 | |
44A | Human, Saudi arabia | mcr-1 | 4 | 4 | |
6R | Human, Saudi arabia | mcr-1 | 4 | 4 | |
85R | Human, Saudi arabia | mcr-1 | 4 | 8 | |
95R | Human, Saudi arabia | mcr-1 | 4 | 8 | |
96R | Human, Saudi arabia | mcr-1 | 8 | 8 | |
134R | Human, Saudi arabia | mcr-1 | 4 | 4 | |
143R | Human, Saudi arabia | mcr-1 | 8 | 8 | |
LH121 | Human, Laos | mcr-1 | 4 | 4 | |
LH140 | Human, Laos | mcr-1, phoQ E375K | 8 | 8 | |
LH257 | Human, Laos | mcr-1 | 16 | 8 | |
LH57 | Human, Laos | mcr-1, phoQ E375K | 4 | 4 | |
LH1 | Human, Laos | mcr-1 | 4 | 4 | |
LH30 | Human, Laos | mcr-1 | 4 | 4 | |
LH345.2 | Human, Laos | mcr-1 | 4 | 4 | |
TH214 | Human, Thailand | mcr-1 | 4 | 8 | |
TH99 | Human, Thailand | mcr-1 | 16 | 16 | |
TH169.1 | Human, Thailand | mcr-1 | 4 | 4 | |
TH259.1 | Human, Thailand | mcr-1 | 4 | 4 | |
TH33.1 | Human, Thailand | mcr-1 | 4 | 4 | |
TH44.1 | Human, Thailand | mcr-1 | 4 | 4 | |
TH66.1 | Human, Thailand | mcr-1 | 4 | 8 | |
TH134.1 | Human, Thailand | mcr-1 | 4 | 4 | |
FHM128.1 | Human, France | mcr-1 | 4 | 4 | |
FHM66.1 | Human, France | mcr-1 | 4 | 4 | |
P4.5 t3 (4) | Pig, Lebanon | mcr-1 | 8 | 4 | |
P1.2 (16) | Pig, Lebanon | mcr-1 | 4 | 4 | |
P1.38 (18) | Pig, Lebanon | mcr-1 | 4 | 4 | |
P1.5 t2 (8) | Pig, Lebanon | mcr-1 | 4 | 4 | |
P2.12 (13) | Pig, Lebanon | mcr-1 | 4 | 4 | |
P2.13 t1 (11) | Pig, Lebanon | mcr-1 | 4 | 4 | |
P2.13 t2 (12) | Pig, Lebanon | mcr-1 | 4 | 4 | |
P2.3 t2 (15) | Pig, Lebanon | mcr-1 | 4 | 4 | |
P2.6 (14) | Pig, Lebanon | mcr-1 | 4 | 4 | |
P4.21 t1 (7) | Pig, Lebanon | mcr-1 | 4 | 4 | |
P4.5 t1 (1) | Pig, Lebanon | mcr-1 | 4 | 4 | |
12 | Environmental, Algeria | mcr-1 | 8 | 8 | |
14 | Environmental, Algeria | mcr-1 | 8 | 8 | |
28 | Environmental, Algeria | mcr-1 | 8 | 8 | |
31 | Environmental, Algeria | mcr-1 | 8 | 8 | |
3 | Environmental, Algeria | mcr-1 | 4 | 4 | |
5 | Environmental, Algeria | mcr-1 | 4 | 4 | |
10 | Environmental, Algeria | mcr-1 | 4 | 8 | |
15 | Environmental, Algeria | mcr-1 | 4 | 4 | |
39 | Environmental, Algeria | mcr-1 | 4 | 4 | |
MCR-2 | Pig, Belgium | mcr-2 | 4 | 4 | |
16 | Environmental, Algeria | mcr-3 | 8 | 4 | |
8 | Environmental, Algeria | mcr-3 | 4 | 8 | |
FHA102 | Human, France | pmrB A159V | 16 | 16 | |
FHM19 | Human, France | pmrB P7-Q12 del (6 aa) | 16 | 8 | |
FHA113 | Human, France | pmrB T156K | 8 | 8 | |
NH94 | Human, Nigeria | pmrB I92 insertion | 16 | 16 | |
LH345.1 | Human, Laos | 4 | 4 | ||
LH53 | Human, Laos | 4 | 4 | ||
TH176 | Human, Thailand | 8 | 8 | ||
TH169.5 | Human, Thailand | 4 | 4 | ||
LB4 | Human, France | 8 | 8 | ||
235 | Chicken, Algeria | mcr-1 | 4 | 4 | |
P6 | Pig, Laos | mcr-1 | 4 | 4 | |
P10 | Pig, Laos | mcr-1 | 4 | 8 | |
P17 | Pig, Laos | mcr-1 | 8 | 4 | |
P7 | Pig, Laos | 4 | 4 | ||
ATCC 25922 | Human, Unknown | 0.5 | 0.25 | ||
ATCC 35218 | Unknown | 1 | 0.5 | ||
EC1 | Human, France | 0.5 | 0.25 | ||
EC2 | Human, France | 0.5 | 0.5 | ||
EC3 | Human, France | 0.5 | 0.25 | ||
EC4 | Human, France | 1 | 0.5 | ||
LH165S* | Human, Laos | 1 | 0.25 | ||
TH77S | Human, Thailand | 0.5 | 0.25 | ||
282S | Chicken, Algeria | 1 | 1 | ||
161 | Chicken, Algeria | 1 | 0.5 | ||
NDM-1 | Human, Israël | 0.5 | 0.25 | ||
Klebsiella pneumoniae | FHA60 | Human, France | mcr-1 | 16 | 16 |
FHM128 | Human, France | mcr-1 | 16 | 8 | |
119R | Human, Saudi arabia | mcr-1 | 8 | 8 | |
LH131 | Human, Laos | mcr-1, mgrb stop | 32 | 32 | |
LH61 | Human, Laos | mcr-1, mgrB sub A14S | 32 | 32 | |
LH17 | Human, Laos | mcr-1, pmrB T157P | 32 | 32 | |
LH92 | Human, Laos | mcr-1 | 16 | 16 | |
LH94 | Human, Laos | mcr-3 | 32 | 32 | |
TH68 | Human, Thailand | mcr-3 | 64 | 64 | |
LH102 | Human, Lao | mcr-3 | 16 | 32 | |
LH375 | Human, Lao | mcr-3 | 16 | 16 | |
TH114 | Human, Thailand | mcr-3 | 16 | 16 | |
TH164 | Human, Thailand | mcr-3 | 16 | 16 | |
LB1 | Human, France | mgrB Stop | 64 | 64 | |
FHM169 | Human, France | mgrB Stop | 16 | 16 | |
LH12 | Human, Laos | mgrB Stop | 32 | 32 | |
TH28 | Human, Thailand | mgrB IS2 | 32 | 32 | |
TH54 | Human, Thailand | pmrB T157P | 16 | 16 | |
TH224 | Human, Thailand | pmrB T157P | 8 | 16 | |
TH205 | Human, Thailand | 8 | 8 | ||
FHM120 | Human, France | 32 | 32 | ||
FHA105 | Human, France | 64 | 64 | ||
FHM77 | Human, France | 16 | 16 | ||
LB3 | Human, France | > 64 | > 64 | ||
SB11R | Human, France | > 64 | > 64 | ||
SB12R | Human, France | > 64 | > 64 | ||
LH140 | Human, Laos | 64 | 64 | ||
KP1PC | Human, France | 16 | 16 | ||
KP2PC | Human, France | 16 | 16 | ||
4321 | Human, UK | 32 | 32 | ||
K39 | Human, Greece | > 64 | 64 | ||
K76 | Human, Greece | > 64 | > 64 | ||
1172/0 | Human, Greece | 32 | 32 | ||
7E | Human, Greece | 32 | 32 | ||
18E | Human, Greece | 16 | 16 | ||
28E | Human, Greece | 16 | 16 | ||
9980 | Human, Greece | 16 | 16 | ||
K77 | Human, Greece | 16 | 16 | ||
1E | Human, Greece | 8 | 8 | ||
KAT3 | Human, Greece | 8 | 8 | ||
2017–10 | Human, Greece | 1 | 0.5 | ||
1678 | Human, Greece | 0.5 | 1 | ||
56 | Human, Greece | 0.5 | 0.25 | ||
K72 | Human, Greece | 0.5 | 0.5 | ||
KP1 | Human, France | 0.5 | 0.25 | ||
KP6 | Human, France | 0.5 | 0.25 | ||
TH28S | Human, Thailand | 0.5 | 0.25 | ||
CIP 82.91 | Unknown | 0.25 | 0.25 | ||
LB2* | Human, France | 1 | 0.25 | ||
ATCC 700603 | Human, UK | 0.5 | 0.25 | ||
Klebsiella oxytoca | FHA41 | Human, France | mgrB IS1 | 32 | 64 |
FHA124 | Human, France | 16 | 32 | ||
TH44* | Human, Thailand | 0.5 | 0.125 | ||
KOX1 | Human, France | 0.5 | 0.25 | ||
Enterobacter aerogenes | EA1509E | Human, France | pmrA G157A | > 64 | > 64 |
SB7R | Human, France | 32 | 16 | ||
EAE1 | Human, France | 0.5 | 0.25 | ||
EAE2 | Human, France | 1 | 0.5 | ||
Enterobacter asburiae | LH74 | Human, Laos | > 64 | > 64 | |
TH66 | Human, Thailand | 32 | 64 | ||
1502 | Human, France | 0.5 | 0.25 | ||
1503 | Human, France | 0.5 | 0.25 | ||
Enterobacter cloacae | SB1 | Human, France | mcr-1 | 4 | 4 |
NH131 | Human, Nigeria | > 64 | > 64 | ||
NH132 | Human, Nigeria | > 64 | > 64 | ||
NH52 | Human, Nigeria | > 64 | > 64 | ||
SB5R | Human, France | > 64 | > 64 | ||
SB6R | Human, France | > 64 | > 64 | ||
SB10R | Human, France | > 64 | 64 | ||
SB4R | Human, France | 64 | 64 | ||
TH66 | Human, Thailand | 32 | 32 | ||
SB3R* | Human, France | 2 | 0.25 | ||
SB2R | Human, France | 2 | 2 | ||
SB5S | Human, France | 2 | 1 | ||
SB1S* | Human, France | 1 | 0.25 | ||
SB2S* | Human, France | 1 | 0.25 | ||
SB3S* | Human, France | 1 | 0.25 | ||
P7698* | Human, France | 1 | 0.25 | ||
NH151 | Human, Nigeria | 0.5 | 0.25 | ||
NH74 | Human, Nigeria | 0.5 | 0.25 | ||
Salmonella enterica | 100RC3 | Human, Saudi Arabia | pmrB deletion (12aa) | 8 | 8 |
65R | Human, Saudi Arabia | pmrB deletion (12aa) | 8 | 8 | |
122R | Human, Saudi Arabia | 1 | 0.5 | ||
108R | Human, Saudi Arabia | 1 | 0.5 | ||
10A | Human, Saudi Arabia | 1 | 1 | ||
Hafnia alvei | B42 | Bird, France | 8 | 8 | |
P516 | Human, France | 8 | 8 | ||
A63 | Bird, France | 4 | 4 | ||
B11 | Bird, France | 4 | 8 | ||
B21 | Bird, France | 4 | 8 | ||
B47 | Bird, France | 4 | 4 | ||
B59 | Bird, France | 4 | 4 | ||
B02 | Bird, France | 4 | 4 | ||
B04 | Bird, France | 4 | 4 | ||
Morganella morgannii | FHA60 | Human, France | > 64 | > 64 | |
Proteus mirabilis | NDM-1 | Human, Israel | > 64 | > 64 | |
Providencia alcalifaciens | TH66 | Human, Thailand | > 64 | > 64 | |
Providencia rettgeri | TH66 | Human, Thailand | > 64 | > 64 | |
Serratia marcescens | P6 | Chicken, Algeria | > 64 | > 64 | |
Stenotrophomonas maltophilia | SM10 | Human, France | > 64 | > 64 | |
SM7 | Human, France | 32 | 16 | ||
SM8 | Human, France | 32 | 32 | ||
SM9 | Human, France | 32 | 32 | ||
SM6 | Human, France | 16 | 16 | ||
SM4 | Human, France | 8 | 8 | ||
SM5 | Human, France | 8 | 8 | ||
SM2 | Human, France | 4 | 4 | ||
SM3 | Human, France | 4 | 4 | ||
SM1 | Human, France | 1 | 1 | ||
Pseudomonas aeruginosa | FHM-PACOLR1 | Human, France | > 64 | > 64 | |
ATCC 27853 | Human, unknown | 1 | 1 | ||
FHM_PA7 | Human, France | 1 | 1 | ||
FHM-PA2 | Human, France | 2 | 2 | ||
FHM-PA3 | Human, France | 2 | 2 | ||
FHM-PA4 | Human, France | 1 | 1 | ||
FHM-PA5 | Human, France | 1 | 1 | ||
FHM-PA6 | Human, France | 1 | 1 | ||
PA1 | Human, France | 0.5 | 0.5 | ||
PA2 | Human, France | 1 | 1 | ||
PA3 | Human, France | 1 | 2 | ||
PA4 | Human, France | 0.5 | 0.25 | ||
PA5 | Human, France | 1 | 1 | ||
PA6 | Human, France | 0.5 | 0.25 | ||
PA7 | Human, France | 1 | 1 | ||
Pseudomonas putida | AEM06 | Environmental, France | 1 | 0.5 | |
AEM10 | Environmental, France | 1 | 0.5 | ||
AEM15 | Environmental, France | 1 | 0.5 | ||
ETP11 | Environmental, France | 0.5 | 0.5 | ||
AEM08 B | Environmental, France | 0.5 | 0.5 | ||
AEM12 | Environmental, France | 0.5 | 0.5 | ||
AEM13 | Environmental, France | 0.5 | 0.5 | ||
AEM16 | Environmental, France | 0.5 | 0.5 | ||
AEM17 A | Environmental, France | 0.5 | 0.5 | ||
AEM17 B | Environmental, France | 0.5 | 0.25 | ||
AEM19 | Environmental, France | 0.5 | 0.25 | ||
PLC009 | Environmental, France | 0.5 | 0.25 | ||
Pseudomonas stutzeri | AEM05 | Environmental, France | 0.25 | 0.5 | |
Pseudomonas sp. | AEM08 A | Environmental, France | 1 | 0.5 | |
AEM07 | Environmental, France | 0.5 | 0.5 | ||
AEM20 | Environmental, France | 0.25 | 0.5 | ||
Acinetobacter baumannii | ABIsac_ColiR | Human, France | pmrA E8D | 64 | 64 |
AB3 | Human, France | 4 | 4 | ||
AB9* | Human, France | 2 | 0.25 | ||
4322 | Human, UK | 1 | 1 | ||
Big | Human, Iran | 1 | 0.5 | ||
Small | Human, Iran | 1 | 0.5 | ||
AB1 | Human, France | 1 | 0.5 | ||
AB2 | Human, France | 1 | 0.5 | ||
AB4 | Human, France | 1 | 0.5 | ||
AB5 | Human, France | 1 | 0.5 | ||
NDM-1* | Human, Lebanon | 1 | 0.25 | ||
AB6* | Human, France | 1 | 0.25 | ||
AB8* | Human, France | 1 | 0.25 | ||
AB10* | Human, France | 1 | 0.25 | ||
CR17 | Human, Spain | 0.5 | 0.5 | ||
Acinetobacter nosocomialis | ABG13S | Human, Spain | 1 | 0.5 | |
Acinetobacter pitti | G867* | Human, France | 1 | 0.25 | |
Acinetobacter sp. | LH213 | Human, Laos | 1 | 1 | |