Table 3 Sequence homology between vaccine candidate peptides of Mtb and Mi

1.

Rv0200 (+)

LVLLVVEGVAINFWLLRRD

⁴⁵LLITQGMAINAYLARRD⁶¹

Possible membrane protein, Rv0200

14/17 (82%)

2.

Rv0200 (+)

QAARALRVTLTKRGSGWLV

²⁰³QSVLALRLTLAKHDGRWLV²²¹

Possible membrane protein, Rv0200

12/19 (63%)

3.

Rv1280C (+)

DGYQDNSGVVAYNPEQAKRE

⁷⁸⁰DGYQDEWAAVLADPDKLRR⁷⁹⁸

Nitrite reductase [NAD(P)H] large subunit

12/19 (63%)

4.

Rv3630

LTRAPLLVPLTAMQGNLIAH

²⁷¹ LTRAPLLVPLTALQGNLIAH²⁹⁰

Possible membrane protein

20/20 (100%)

5.

Rv3630

LTRAPLLVPLTAMQGNLIAH

⁴LTPLPVLIPLTAAALTLIA²²

Na(+) H(+) antiporter subunit D

13/19 (68%)

6.

Rv0418 (+)

LKMAGKTAQDTSFDGRSDYD

³⁸⁸LAEQGKKAHDTGYDGRSDYD⁴⁰⁷

Aminopeptidase Y (Arg, Lys, Leu preference) (EC 3.4.11.15)

14/20 (70%)

7.

Rv0418 (+)

LKMAGKTAQDTSFDGRSDYD

³⁸⁹LNLAGKRPAAEEFSGRSDY⁴⁰⁷

Aminopeptidase Y (Arg, Lys, Leu preference) (EC 3.4.11.15)

11/19 (57%)

8.

Rv0418 (+)

VAAPADDSPGCSPSDYDRLP

¹⁴⁴VPARAEESPGCTVEDYDGL¹⁶²

Aminopeptidase Y (Arg, Lys, Leu preference) (EC 3.4.11.15)

14/19 (73%)

9.

Rv0418 (+)

VAAPADDSPGCSPSDYDRLP

²⁸AAADDPPNCTPAD⁴⁰

Exported protein

10/13 (76%)

10.

Rv1022

DGIANVDNIDDAALSAAGYL

¹⁹³DGEPSPDNIDDAALSAAGYL²¹²

Lipoprotein LpqU

17/20 (85%)

11.

Rv0566 (+)

TPDRITYRPQLGVLYPSELS

⁵¹TPERVTYRPELGVLYPSELS⁷⁰

Possible membrane protein

20/20 (100%)

12.

Rv0566 (+)

TPDRITYRPQLGVLYPSELS

¹⁷⁷DAIAYLPEFGVLYAGDL¹⁹³

Fumarylacetoacetase (EC 3.7.1.2)

11/17 (64%)

13.

Rv0361

DAETETVVITTSDNDAAVTQ

¹⁸⁹SEGRTVVLTTHDMDEAVS²⁰⁶

ABC transporter, ATP-binding protein

13/18 (72%)

14.

Rv0361

RSLDLQFRDDQWKITQSSSN

²⁴²RSFDLQFRDNQWKICQS²⁵⁸

Probable conserved membrane protein

15/17 (88%)

15.

Rv1326c (−)

MSRSEKLTGEHLAPEPAEMA

³⁴⁸ERLTVEHALPSPAEL³⁶²

NTD biosynthesis operon putative oxidoreductase NtdC

11/15 (73%)

16.

Rv1326c (−)

RFDGTPLYEHSDPKRGEQLD

³⁵⁹RFDGTPLYEHADPHRAEQLD³⁷⁸

1,4-alpha-glucan (glycogen) branching enzyme, GH-13-type (EC 2.4.1.18)

18/20 (90%)