Table 1 In vitro antibacterial activity of cationic antimicrobial peptides against methicillin-resistant and -susceptible S. aureus, and antibiotic susceptible and multidrug-resistant P. aeruginosa
CAMPs | S. aureus (number) | MIC (μg/ml) | MBC (μg/ml) | P. aeruginosa (number) | MIC (μg/ml) | MBC (μg/ml) |
|---|---|---|---|---|---|---|
LL-37 | MSSA (5) | > 128 | > 128 | AS (6) | 32-64 | 32-64 |
MRSA (5) | > 128 | > 128 | MDRPA (5) | 32-64 | 32-64 | |
CAMA | MSSA (5) | 2-4 | 4 | AS (6) | 4-8 | 4-8 |
MRSA (5) | 4 | 4 | MDRPA (5) | 4-8 | 4-8 | |
Magainin-II | MSSA (5) | > 128 | > 128 | AS (6) | 128- > 128 | 128- > 128 |
MRSA (5) | > 128 | > 128 | MDRPA (5) | > 128 | > 128 | |
Nisin | MSSA (5) | > 128 | > 128 | AS (6) | > 128 | > 128 |
MRSA (5) | > 128 | > 128 | MDRPA (5) | > 128 | > 128 |