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Fig. 4 | BMC Microbiology

Fig. 4

From: Lactobacillus mucosae DPC 6426 as a bile-modifying and immunomodulatory microbe

Fig. 4

Putative Mechanisms Through Which Lactobacillus mucosae DPC 6426 May Exert Cardio-protective Effects. Black text indicates results which are reported in the present study, while grey text represents extrapolations of the potential in vivo effects of such physiological reactions to Lactobacillus mucosae DPC 6426 and its metabolites, in the context of cardiovascular disease. cBA, conjugated bile acids; FXR, farnesoid X receptor; FGF15, fibroblast growth factor 15; CHO, cholesterol; BSH, bile salt hydrolase; EPS, exopolysaccharide; SEC, secretome; M1, classically activated macrophage; M2, alternatively activated macrophage; IL-10, interleukin-10; CD206, cluster of differentiation 206; NO, nitric oxide; ROS, reactive oxygen species; DC, dendritic cell

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