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Table 3 Patients’ characteristics grouped by colonisation status (non- community B vs. community B) and subdivided by the time-point of occurrence (pre- and/or postoperative period)

From: Gut microbiome patterns correlate with higher postoperative complication rates after pancreatic surgery

 

Pre and post community B

Post community B

p-value pre and post community B vs. post community B

Number

7

12

 

Age [years]

64.0 (58.5–67.0)

70.0 (58.5–75.0)

0.445

ASA status

2.0 (2.0–2.5)

3.0 (2.0–3.0)

0.118

Cardiovascular risk factors

 Coronary heart disease

0 (0.0%)

2 (16.7%)

0.253

 Diabetes

2 (28.6%)

3 (25.0%)

0.865

 Arterial hypertension

2 (28.6%)

6 (50.0%)

0.361

 Chronic renal failure

0 (0.0%)

0 (0.0%)

1.000

Primary disease

 Malignant

4 (57.1%)

9 (75.0%)

0.419

 IPMN

3 (42.9%)

2 (16.7%)

0.211

 Chronic pancreatitis

0 (0.0%)

1 (8.3%)

0.433

Operation

 Partial pancreaticoduodenectomy

4 (57.1%)

3 (25.0%)

0.161

 Pylorus-preserving pancreas head resection

1 (14.3%)

5 (41.7%)

0.216

 Total pancreatectomy

1 (14.3%)

0 (0.0%)

0.179

 Distal pancreatectomy

1 (14.3%)

2 (16.7%)

0.891

 Tumour enucleation

0 (0.0%)

2 (16.7%)

0.253

 Surgery [min]

330.0 (315.0–360.0)

240.0 (176.3–333.8)

0.149

 Blood loss1 [mL]

750.0 (600.0–1300.0)

600.0 (500.0–800.0)

0.251

 Infusion1 [mL]

3000.0 (2750.0–4250.0)

3000.0 (2375.0–3750.0)

0.491

 Transfusion1 [mL]

0.0 (0.0–0.0)

0.0 (0.0–0.0)

1.000

 CRP2 [mg/L]

147.5 (79.2–175.8)

86.7 (45.5–148.0)

0.178

 Leucocytes2 [1/nL]

12.5 (8.6–14.0)

10.4 (8.0–12.9)

0.370

Hospital stay

 In total [days]

15.0 (10.5–32.0)

16.0 (11.8–33.8)

0.641

 Intermediate care unit [days]

0.0 (0.0–5.5)

0.0 (0.0–0.3)

0.539

 Intensive care unit [days]

1.0 (0.0–1.5)

0.0 (0.0–1.0)

0.295

Postoperative complications [Clavien-Dindo classification]

 Grade I

3 (42.9%)

2 (16.7%)

0.211

 Grade II

1 (14.3%)

5 (41.7%)

0.363

 Grade III3

0 (0.0%)

2 (16.7%)

0.253

 Grade IV4

0 (0.0%)

0 (0.0%)

1.000

 Grade V

1 (14.3%)

1 (8.3%)

0.683

Outcome

 Survivor 90 days

13 (100.0%)

19 (100.0%)

1.000

  1. Data are presented as the median and interquartile range (Q1–Q3) or as count and percentage. A p-value < 0.05 was considered statistically significant and are highlighted in boldface. Concerning symbolism and higher orders of significance: p < 0.05 *, p < 0.01 **, p < 0.001 ***. ASA status, American Society of Anesthesiologists physical status classification system; IPMN, intraductal papillary mucinous neoplasm; CRP, C-reactive protein. 1total measured intraoperatively; 2postoperative observation period; 3includes grades IIIa and IIIb; 4includes grades IVa and IVb