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Table 3 The factorial design runs in Design Expert for three selected levels of the three tested factors inoculum size, pH and incubation period

From: Paromomycin production from Streptomyces rimosus NRRL 2455: statistical optimization and new synergistic antibiotic combinations against multidrug resistant pathogens

Run Order

pH (A)

Inoculum size (B, %)

Incubation period (C, days)

1

9

1

6

2

7.5

5.5

6

3

9

5.5

3

4

7.5

5.5

6

5

6

5.5

9

6

7.5

1

9

7

7.5

5.5

6

8

9

10

6

9

7.5

5.5

6

10

6

1

6

11

6

10

6

12

7.5

10

3

13

7.5

1

3

14

6

5.5

3

15

7.5

5.5

6

16

7.5

10

9

17

9

5.5

9

Factor

Name

Level (−1)

level (+ 1)

A

pH

6

9

B

inoculum size (%)

1

10

C

incubation period (days)

3

9