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Fig. 1 | BMC Microbiology

Fig. 1

From: In vitro synergy of sertraline and tetracycline cannot be reproduced in pigs orally challenged with a tetracycline resistant Escherichia coli

Fig. 1

Total fecal (_F) and intestinal (_I) tetracycline resistant CFU Numbers (in log10 CFU per gram feces (_F) or ileum (_I)) of total tetracycline resistant CFU at different time points in four different treatment groups. Vertical bars indicate standard deviations. Timepoint T(− 2) refers to two days before treatment start, and just prior to oral inoculation of all pigs with a tetracycline/rifampicin resistant Escherichia coli strain. At T(− 2) 12 individual fecal samples were obtained from each group. No pigs were euthanized at this point, therefore no ileum samples were obtained at T(− 2). Time point T(0) refers to the first treatment day. Samples were obtained prior to the first treatment at the same day. From each group 12 individual fecal samples were obtained. Hereafter, two pigs were euthanized at ileum samples were obtained from 2X4 pigs. Time T(7) refers to 48 h after the last of five days of treatment. From each group 10 individual fecal samples were obtained. Hereafter, five pigs were euthanized and ileum samples were obtained from 5X4 pigs. Time T(9) refers to nine days after the last of five days of treatment. From each group five individual fecal samples were obtained. Hereafter, the five pigs in each group were euthanized and ileum samples were obtained from 5X4 pigs. For visual purposes all CFU counts at the different time points has been included in the same figure, statistical analysis were, however, done for each time point, each treatment group at different sampling time and sampling site (fecal or ileum) individually. Asterisks over straight lines indicate a statistical difference at the same time point between treatment groups. Arrows indicate statistical difference at the different time points within each treatment groups. Hash tag indicates that group is statistically different from the other groups at the same sampling time. Statistical significant differences between fecal and ileum samples are not shown on the figure

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