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Table 2 Clinical and biological data of the patients according to the E. coli O1K1 subgroups

From: Genome sequencing of strains of the most prevalent clonal group of O1:K1:H7 Escherichia coli that causes neonatal meningitis in France

Clinical and biological characteristics

Prevalence of characteristics among the following subgroups:

 

D-1 (n = 28)

A + D-2 + D-3a (n = 10)

p value*

Gender (M/W)

12/14 (26)

5/3 (8)

0.69

Median of term (AW)

37 [29–41] (20)

39 [34–41] (6)

0.18

Median of birth weight (grams)

3160 [950–3630] (19)

3555 [2260–4240] (6)

0.13

Median of age at the LP (days)

13.5 [1–136] (28)

28 [3–145] (9)

0.25

Median of CSF glucose (mmol/l)

0.4 [0–3.6] (12)

1.9 [0.4–3.4] (4)

0.22

Median of CSF protein (g/l)

2.2 [0.7–5.1] (12)

1.6 [1.1–10] (3)

1

Median of number of cells in CSF (/mm3)

9300 [800–60,000] (12)

1320 [60–3158] (4)

0.02

Median of neutrophil polynuclear % in CSF

85 [72–95] (9)

92 [90–95] (3)

0.48

% of Positive blood culture

54 (11)

50 (4)

1

  1. Values in parentheses correspond to the number of patients for whom information as available
  2. Values in brackets correspond to minimum and maximum
  3. *Fisher’s exact test was used for comparison of proportion and categorical variables
  4. *Mann-Whitney test was used for comparison of median and continuous variables
  5. aSubgroup A and clusters D-2 and D-3 have been merged for the statistical analysis