Genome sequencing of strains of the most prevalent clonal group of O1:K1:H7 Escherichia coli that causes neonatal meningitis in France

Table 1 Distribution of putative virulence factors and bacteriocins detected in silico among O1:K1 NMEC strains

Genes	Rate (%) among STc95 subgroups/clusters
Genes	A (n = 4)	D-1 (n = 28)	D-2/D-3^b (n = 6)	Total (N = 38)
Adhesins
papGII	100	100	100	100
iha	0	3.6	100	18.4
Iron transport
iucC, iutA	25	92.6	100	86.8
fyuA, irp	100	100	100	100
iroN, D	50	100	100	94.7
chuA	100	100	100	100
sitA	75	100	100	97.4
Bacteriocins
cvaA, C	50	100	0	78.9
cvi	50	100	100	94.7
cia	0	100	0	73.7
imm	50	100	0	78.9
mchB, C	0	3.6	0	2.6
mchF	50	100	0	78.9
ColV plasmid related
tsh	25	0	0	2.6
etsC	50	100	0	78.9
ompTp^a	50	100	0	78.9
hlyF	50	100	0	78.9
mig-14	50	100	0	78.9
iss^a	50	100	0	78.9
traj	0	100	0	73.7
eitB	25	0	0	2.6
Toxin
hlyC	0	0	100	15.8
clbB, N	100	0	0	10.5
sat	0	0	100	15.8
vat	75	92.6	100	92.1
senB	50	0	0	5.3
Others
epeA	0	3.6	0	2.6
ireA	100	100	100	100
gad	100	100	100	100

^a: plasmidic genes
^b: D-2 and D-3 clusters have been merged since they harbor identical genetic determinants except for fimH (Fig. 2)
Only virulence genes present at least in one strain are indicated, other genes not detected are not shown [see Additional file 4]

ISSN: 1471-2180