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Table 1 Characteristics of complex SVs in HBV

From: Characterization of hepatitis B virus with complex structural variations

Sequence gap in complex SVs

56/70 (80.0%)

SVs in complex SVs

 Insertion (+)

65/70 (92.9%)

 Deletion (+)

64/70 (91.4%)

 Duplication (+)

18/70 (25.7%)

Types of insertion

(n = 65)

 A. HNF1 binding site

32 (49.2%)

 B. Insertion of unknown origin (X-1)

12 (18.5%)

 C. Insertion of unknown origin (X-2)

4 (6.2%)

 D. Sequence complementary to part of box α in enhancer II

6 (9.2%)

 E. Miscellaneous

11 (16.9%)

  1. SV structural variation, HNF1 hepatocyte nuclear factor 1