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Table 2 Time (in hours) required to determine susceptibility of susceptible Y. pestis strains by optical screening and summary of categorical agreement for AST results by optical screening and conventional BMD for all strains

From: Rapid antimicrobial susceptibility testing and β-lactam-induced cell morphology changes of Gram-negative biological threat pathogens by optical screening

  1. For susceptible Y. pestis strains, the time (in hours) required to determine susceptibility by optical screening is described with a confidence level of 95% (p-value ≤0.05). The categorical agreement for susceptibility to GEN, DOX, and CIP for all strains is summarized. Concentrations in blue are equal to the CLSI breakpoint for susceptibility. Strains were grown over an 18 h period and time measurements represent the mean ± standard deviation of duplicate biological experiments (n = 3). The number of (S) susceptible, (R) resistant, and (NS) non-susceptible strains, the percentage of categorical agreement and the percentage of error (very major and major) are displayed. DSJB001 was the resistant/non-susceptible strain evaluated