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Table 1 Bacterial strains used in this study and their antimicrobial susceptibility profiles

From: Rapid antimicrobial susceptibility testing and β-lactam-induced cell morphology changes of Gram-negative biological threat pathogens by optical screening

  Minimal Inhibitory Concentration
B. pseudomallei Description Origin Country Year Ref AMC CAZ IPM SXT DOX
 Bp82 attenuated Laboratory USA 2010 [45] ≤ 4/2 (S) ≤ 4 (S) ≤ 2 (S) ≤ 0.5/9.5 (S) ≤ 1 (S)
 JB039 attenuated; derivative of Bp82 Laboratory USA 2016 [49] 32/16 (R) >  128 (R) 64 (R) >  32/608 (R) 32 (R)
 ATCC 23343 wild-type Human n/a < 1957 [72] 2/1 (S) 1 (S) 0.25 (S) 0.5/9.5 (S) 0.5 (S)
 PHLS 14 wild-type Monkey Philippines 1990 [73, 74] 4/2 (S) 2 (S) 0.25 (S) 2/38 (S) 1 (S)
 B7210 wild-type Human Australia 1970 [74, 75] 4/2 (S) 2 (S) 0.5 (S) 1 (S) 2 (S)
 Bp1651 wild-type Human USA n/a [76] 64/32 (R) > 128 (R) 32 (R) > 32/608 (R) 16 (R)
B. mallei Description Origin Country Year Ref CAZ IPM DOX  
 ATCC 23344 wild-type Human China 1942 [72, 74] 1 (S) ≤ 1 (S) ≤ 0.25 (S)
 NCTC 10260 wild-type Human Turkey 1949 [72, 74] 4 (S) ≤ 1 (S) ≤ 0.25 (S)
 Turkey 5 wild-type Human Turkey n/a [74, 77] 4 (S) ≤ 1 (S) ≤ 0.25 (S)
 KC 1092 wild-type Mule Iran 1952 [53, 74, 78] 4 (S) ≤ 1 (S) ≤ 0.25 (S)
Y. pestis Description Origin Country Year Ref GEN DOX CIP
 A1122 attenuated Laboratory USA 1943 [79] 0.5 (S) 2 (S) 0.03 (S)
 DSJB001 attenuated; derivative of A1122 Laboratory USA 2016 [49] 32 (R) >  32 (R) 4 (NS)
 Antiqua wild-type; biovar Antiqua Human Congo 1965 [80, 81] 0.25 (S) 0.5 (S) 0.03 (S)
 Java 9 wild-type; biovar Orientalis Rat Indonesia 1957 [80, 82] 0.5 (S) 1 (S) 0.06 (S)
 Nicholisk 41 wild-type; biovar Medievalis Unknown China 1940 [80] 0.06 (S) 0.25 (S) ≤ 0.03 (S)
 Angola wild-type; pestoides group Unknown Angola <  1984 [80, 83] 0.5 (S) 0.25 (S) 0.015 (S)
  1. Antimicrobial susceptibility profiles were determined by conventional BMD testing based on CLSI guidelines and minimal inhibitory concentrations (MICs) were recorded in the unit of μg/ml. Susceptible (S), non-susceptible (NS), resistant (R)