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Table 1 Bacterial strains used in this study and their antimicrobial susceptibility profiles

From: Rapid antimicrobial susceptibility testing and β-lactam-induced cell morphology changes of Gram-negative biological threat pathogens by optical screening

 

Minimal Inhibitory Concentration

B. pseudomallei

Description

Origin

Country

Year

Ref

AMC

CAZ

IPM

SXT

DOX

 Bp82

attenuated

Laboratory

USA

2010

[45]

≤ 4/2 (S)

≤ 4 (S)

≤ 2 (S)

≤ 0.5/9.5 (S)

≤ 1 (S)

 JB039

attenuated; derivative of Bp82

Laboratory

USA

2016

[49]

32/16 (R)

>  128 (R)

64 (R)

>  32/608 (R)

32 (R)

 ATCC 23343

wild-type

Human

n/a

< 1957

[72]

2/1 (S)

1 (S)

0.25 (S)

0.5/9.5 (S)

0.5 (S)

 PHLS 14

wild-type

Monkey

Philippines

1990

[73, 74]

4/2 (S)

2 (S)

0.25 (S)

2/38 (S)

1 (S)

 B7210

wild-type

Human

Australia

1970

[74, 75]

4/2 (S)

2 (S)

0.5 (S)

1 (S)

2 (S)

 Bp1651

wild-type

Human

USA

n/a

[76]

64/32 (R)

> 128 (R)

32 (R)

> 32/608 (R)

16 (R)

B. mallei

Description

Origin

Country

Year

Ref

CAZ

IPM

DOX

 

 ATCC 23344

wild-type

Human

China

1942

[72, 74]

1 (S)

≤ 1 (S)

≤ 0.25 (S)

 NCTC 10260

wild-type

Human

Turkey

1949

[72, 74]

4 (S)

≤ 1 (S)

≤ 0.25 (S)

 Turkey 5

wild-type

Human

Turkey

n/a

[74, 77]

4 (S)

≤ 1 (S)

≤ 0.25 (S)

 KC 1092

wild-type

Mule

Iran

1952

[53, 74, 78]

4 (S)

≤ 1 (S)

≤ 0.25 (S)

Y. pestis

Description

Origin

Country

Year

Ref

GEN

DOX

CIP

 A1122

attenuated

Laboratory

USA

1943

[79]

0.5 (S)

2 (S)

0.03 (S)

 DSJB001

attenuated; derivative of A1122

Laboratory

USA

2016

[49]

32 (R)

>  32 (R)

4 (NS)

 Antiqua

wild-type; biovar Antiqua

Human

Congo

1965

[80, 81]

0.25 (S)

0.5 (S)

0.03 (S)

 Java 9

wild-type; biovar Orientalis

Rat

Indonesia

1957

[80, 82]

0.5 (S)

1 (S)

0.06 (S)

 Nicholisk 41

wild-type; biovar Medievalis

Unknown

China

1940

[80]

0.06 (S)

0.25 (S)

≤ 0.03 (S)

 Angola

wild-type; pestoides group

Unknown

Angola

<  1984

[80, 83]

0.5 (S)

0.25 (S)

0.015 (S)

  1. Antimicrobial susceptibility profiles were determined by conventional BMD testing based on CLSI guidelines and minimal inhibitory concentrations (MICs) were recorded in the unit of μg/ml. Susceptible (S), non-susceptible (NS), resistant (R)