TY - JOUR AU - McLaughlin, Heather P. AU - Sue, David PY - 2018 DA - 2018/12/18 TI - Rapid antimicrobial susceptibility testing and β-lactam-induced cell morphology changes of Gram-negative biological threat pathogens by optical screening JO - BMC Microbiology SP - 218 VL - 18 IS - 1 AB - For Yersinia pestis, Burkholderia pseudomallei, and Burkholderia mallei, conventional broth microdilution (BMD) is considered the gold standard for antimicrobial susceptibility testing (AST) and, depending on the species, requires an incubation period of 16–20 h, or 24–48 h according to the Clinical and Laboratory Standards Institute (CLSI) guidelines. After a diagnosis of plague, melioidosis or glanders during an outbreak or after an exposure event, the timely distribution of appropriate antibiotics for treatment or post-exposure prophylaxis of affected populations could reduce mortality rates. SN - 1471-2180 UR - https://doi.org/10.1186/s12866-018-1347-9 DO - 10.1186/s12866-018-1347-9 ID - McLaughlin2018 ER -