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Fig. 6 | BMC Microbiology

Fig. 6

From: VirB10 vaccination for protection against Anaplasma phagocytophilum

Fig. 6

CD4+ and CD8+ T cell responses from rVirB-vaccinated mice after A. phagocytophilum challenge. Spleen cells from rVirB and control (pcDNA3.1/Ovalbumin)-vaccinated mice were evaluated for intracellular IFN-γ+ and IL-10+ production by flow cytometry. a representative plots, gated for CD4+ and CD8+ T cells, depicting IFN-γ+, IL-10+, and double-positive (IL-10+-IFN-γ+) T cells. b and (c) bar graphs displaying total IFN-γ+, IL-10+, and double-positive (IL-10+, IFN-γ+) CD4+ and CD8+ T cells. *, P = 0.01 to 0.05; **, P = 0.001 to 0.01; ****, P < 0.0001

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