Fig. 8

The expression of PDE2 protein in C. albicans biofilms. a: WT: Farnesol untreated wild strain (CAI4-pCaEXP); WT + F: Farnesol treated wild strain (CAI4-pCaEXP); P: Farnesol untreated PDE2-overexpressing strain (PDE2OE); P + F: Farnesol treated PDE2-overexpressing strain (PDE2OE). a and b: Farnesol increased the expression of PDE2 of the CAI4-pCaEXP strain at 12, 24 and 36 h biofilm phases and increased the expression of PDE2 of the PDE2OE strain at 6, 12, 24 and 36 h biofilm phases compared to the respective untreated controls. Shown are means ± standard deviation of three independent experiments performed in duplicate. One-way analysis of variance (ANOVA) was employed to assess the statistical significance of differences in matched groups, while paired t-tests were performed for intra-group comparisons. *: p < 0.05. **: p < 0.01