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Fig. 4 | BMC Microbiology

Fig. 4

From: The possible molecular mechanisms of farnesol on the antifungal resistance of C. albicans biofilms: the regulation of CYR1 and PDE2

Fig. 4

The level of cAMP from C. albicans biofilms in the presence of farnesol. Farnesol decreased the intracellular cAMP levels in the biofilms of the CYR1OE strain, the PDE2OE strain, and the wild strain compared to those of the respective untreated controls. In addition, compared to the cAMP levels in the wild strain, the cAMP levels in the CYR1OE strain were significantly higher in all studied phases. One-way analysis of variance (ANOVA) was employed to assess the statistical significance of differences in matched groups, while paired t-tests were performed for intra-group comparisons. *: p < 0.05. **: p < 0.01

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