Skip to main content

Table 5 Glycopeptide MICs of the MITC derivatives that had been introduced mutations in vanB gene cluster

From: Dissemination and genetic analysis of the stealthy vanB gene clusters of Enterococcus faecium clinical isolates in Japan

Strain

MIC (mg/L)a

VAN

TEC

M1TC

3

1

M1TC vanSB _E124Ab

4

1

M1TC vanB_ V128Ab

3

1

M1TC vanW_ P92Tb

3

1

M1TC vanSB_ E124A/vanB_ V128Ab

8

1

M1TC vanSB_ E124A/vanW_ P92Tb

8

1

M1TC vanB_ V128A/vanW_ P92Tb

3

1

M1TC vanSB_ E124A/vanB_ V128A/vanW_ P92Tb

16

1

  1. aVAN, vancomycin; TEC, teicoplanin bThree unique substitutions for M1 and Y7
  2. 255 strains were exchanged to that of the reference gene of pMG2200 by pCJK47-used 256 homologous recombination