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Table 2 Single nucleotide variations found in the vanB. gene cluster of E. faecium M1 and Y7

From: Dissemination and genetic analysis of the stealthy vanB gene clusters of Enterococcus faecium clinical isolates in Japan

Gene

Substitutionsb

BM4661a > M1/Y7

vanS B

371C > A

(Ala124Glu)d

vanW

274A > C

(Thr92Pro)d

vanW

392G > T

(Ile131Ser)

vanB

335A > T

(Glu112Val)

vanB

383C > T

(Ala128Val)d

vanB

961A > G

(Met321Val)

vanX B

267 T > C

SMc

  1. aThe genetic information for BM4661 (accession no.; FJ767776.1) was obtained from the genome database in NCBI (http://www.ncbi.nlm.nih.gov/). bThe nucleotide sequences of vanB gene clusters of M1 and Y7 strains were identical. The brackets indicate amino acid substitutions in vanB gene clusters. The numbers of substitutions represent the location of each gene and protein. cSM, synonymous mutation. dUnique substitutions for M1 and Y7 strains (Additional file 2-4: Figures S1–3)