TY - JOUR AU - Plummer, Erica L. AU - Bulach, Dieter M. AU - Murray, Gerald L. AU - Jacobs, Susan E. AU - Tabrizi, Sepehr N. AU - Garland, Suzanne M. AU - Garland, S. M. AU - Jacobs, S. E. AU - Tobin, J. M. AU - Tabrizi, S. N. AU - Pirotta, M. AU - Donath, S. AU - Opie, G. F. AU - Tang, M. L. K. AU - Morley, C. J. AU - Hickey, L. AU - Tan, K. AU - Lewis, A. AU - Veldman, A. AU - Travadi, J. AU - Wright, I. M. R. AU - Osborn, D. A. AU - Sinn, J. AU - Levison, J. AU - Stack, J. A. AU - DePaoli, A. G. AU - Austin, N. C. AU - Darlow, B. A. AU - Alsweiler, J. M. AU - Buksh, M. J. AU - for the ProPrems Study Group PY - 2018 DA - 2018/11/13 TI - Gut microbiota of preterm infants supplemented with probiotics: sub-study of the ProPrems trial JO - BMC Microbiology SP - 184 VL - 18 IS - 1 AB - The ProPrems trial, a multi-center, double-blind, placebo-controlled randomized trial, previously reported a 54% reduction in necrotizing enterocolitis (NEC) of Bell stage 2 or more from 4.4 to 2.0% in 1099 infants born before 32 completed weeks’ gestation and weighing < 1500 g, receiving probiotic supplementation (with Bifidobacterium longum subsp. infantis BB-02, Streptococcus thermophilus TH-4 and Bifidobacterium animalis subsp. lactis BB-12). This sub-study investigated the effect of probiotic supplementation on the gut microbiota in a cohort of very preterm infants in ProPrems. SN - 1471-2180 UR - https://doi.org/10.1186/s12866-018-1326-1 DO - 10.1186/s12866-018-1326-1 ID - Plummer2018 ER -