AMR genes and its role | AMR genes that are present in the strains that are: | |||
---|---|---|---|---|
ISS (n = 5) | 153 ECLO | MBRL 1077 | EB247 | |
Cystine ABC transporter, ATP-binding protein | + | + | + | + |
Cystine ABC transporter, permease protein | + | + | + | + |
D-cysteine desulfhydrase (EC 4.4.1.15) | + | + | + | + |
Spectinomycin 9-O-adenylyltransferase | Â | Â | Â | + |
Streptomycin 3-O-adenylyltransferase (EC 2.7.7.47) | Â | Â | Â | + |
Arsenate reductase (EC 1.20.4.1) | + | + | + | + |
Arsenic efflux pump protein | + | + | + | + |
Arsenic resistance protein ArsH | Â | Â | Â | + |
Arsenical resistance operon repressor | + | + | + | + |
Beta-lactamase (EC 3.5.2.6) | + | + | + | + |
Beta-lactamase class C and other penicillin binding proteins | Â | Â | + | Â |
Metal-dependent hydrolases of the beta-lactamase superfamily I | + | + | + | + |
Cation efflux system protein CusA | + | + | + | + |
Cation efflux system protein CusC precursor | Â | Â | + | + |
Cation efflux system protein CusF precursor | Â | Â | + | + |
Cobalt-zinc-cadmium resistance protein | + | + | + | + |
Cobalt-zinc-cadmium resistance protein CzcA | + | + | + | + |
Cobalt/zinc/cadmium efflux RND transporter, membrane fusion protein, CzcB family | Â | Â | + | + |
Copper-sensing two-component system response regulator CusR | Â | Â | + | + |
DNA-binding heavy metal response regulator | + | + | + | + |
Heavy metal sensor histidine kinase | Â | Â | Â | + |
Probable Co/Zn/Cd efflux system membrane fusion protein | + | + | + | + |
Zinc transporter ZitB | + | + | + | + |
Acetyl-coenzyme A carboxyl transferase beta chain (EC 6.4.1.2) | + | + | + | + |
Amidophosphoribosyltransferase (EC 2.4.2.14) | + | + | + | + |
Colicin V production protein | + | + | + | + |
DedA protein | + | + | + | + |
DedD protein | + | + | + | + |
Dihydrofolate synthase (EC 6.3.2.12) | + | + | + | + |
Folylpolyglutamate synthase (EC 6.3.2.17) | + | + | + | + |
tRNA pseudouridine synthase A (EC 4.2.1.70) | + | + | + | + |
Blue copper oxidase CueO precursor | + | + | + | + |
Copper resistance protein C precursor | + | + | + | + |
Copper resistance protein D | + | + | + | + |
Copper-translocating P-type ATPase (EC 3.6.3.4) | + | + | + | + |
Copper homeostasis protein CutE | + | + | + | + |
Copper homeostasis protein CutF precursor | + | + | + | + |
Magnesium and cobalt efflux protein CorC | + | + | + | + |
Membrane protein, suppressor for copper-sensitivity ScsB | + | + | + | + |
Membrane protein, suppressor for copper-sensitivity ScsD | + | + | + | + |
Secreted protein, suppressor for copper-sensitivity ScsC | + | + | + | + |
Suppression of copper sensitivity: putative copper binding protein ScsA | + | + | + | + |
Fosfomycin resistance protein FosA | + | + | + | + |
Membrane-bound lysozyme inhibitor of c-type lysozyme | + | + | + | + |
16Â kDa heat shock protein A | + | + | + | + |
16Â kDa heat shock protein B | + | + | + | + |
HTH-type transcriptional regulator YidP | + | + | + | + |
Mediator of hyperadherence YidE | + | + | + | + |
Outer membrane lipoprotein YidQ | + | + | + | + |
Uncharacterized protein YidR | + | + | + | + |
Mercuric ion reductase (EC 1.16.1.1) | Â | Â | Â | + |
PF00070 family, FAD-dependent NAD(P)-disulphide oxidoreductase | + | + | + | + |
Mercuric resistance operon coregulator | Â | Â | Â | + |
Mercuric resistance operon regulatory protein | Â | Â | Â | + |
Mercuric transport protein, MerE | Â | Â | Â | + |
Acriflavin resistance protein | + | + | + | + |
Macrolide export ATP-binding/permease protein MacB (EC 3.6.3.-) | + | + | + | + |
Macrolide-specific efflux protein MacA | + | + | + | + |
Membrane fusion protein of RND family multidrug efflux pump | + | + | + | + |
Multi antimicrobial extrusion protein (Na(+)/drug antiporter), MATE family of MDR efflux pumps | + | + | + | + |
Multidrug-efflux transporter, major facilitator superfamily (MFS) (TC 2.A.1) | + | + | + | + |
Probable transcription regulator protein of MDR efflux pump cluster | + | + | + | + |
RND efflux system, inner membrane transporter CmeB | + | + | + | + |
RND efflux system, membrane fusion protein CmeA | + | + | + | + |
RND efflux system, outer membrane lipoprotein CmeC | + | + | Â | + |
RND efflux system, outer membrane lipoprotein, NodT family | + | + | + | + |
Transcription repressor of multidrug efflux pump acrAB operon, TetR (AcrR) family | + | + | + | + |
Type I secretion outer membrane protein, TolC precursor | + | + | + | + |
Inner membrane component of tripartite multidrug resistance system | + | + | + | + |
Membrane fusion component of tripartite multidrug resistance system | + | + | + | + |
Outer membrane component of tripartite multidrug resistance system | + | + | + | + |
Multiple antibiotic resistance protein MarA | + | + | + | + |
Multiple antibiotic resistance protein MarB | + | + | + | + |
Multiple antibiotic resistance protein MarC | + | + | + | + |
Multiple antibiotic resistance protein MarR | + | + | + | + |
DNA-directed RNA polymerase beta subunit (EC 2.7.7.6) | + | + | + | + |
DNA-directed RNA polymerase beta' subunit (EC 2.7.7.6) | + | + | + | + |
LSU ribosomal protein L20p | + | + | + | + |
LSU ribosomal protein L35p | + | + | + | + |
Translation initiation factor 3 | + | + | + | + |
SSU ribosomal protein S12p (S23e) | + | + | + | Â |
SSU ribosomal protein S7p (S5e) | + | + | + | Â |
Translation elongation factor G | + | + | + | Â |
Translation elongation factor Tu | + | + | + | Â |
L-aspartate oxidase (EC 1.4.3.16) | + | + | + | + |
Quinolinate phosphoribosyltransferase [decarboxylating] (EC 2.4.2.19) | + | + | + | + |
Quinolinate synthetase (EC 2.5.1.72) | + | + | + | + |
DNA gyrase subunit A (EC 5.99.1.3) | + | + | + | + |
DNA gyrase subunit B (EC 5.99.1.3) | + | + | + | + |
Topoisomerase IV subunit A (EC 5.99.1.-) | + | + | + | + |
Topoisomerase IV subunit B (EC 5.99.1.-) | + | + | + | + |
Streptothricin acetyltransferase, Streptomyces lavendulae type | + | + | + | + |
Multidrug transporter MdtB | + | + | + | + |
Multidrug transporter MdtC | + | + | + | + |
Multidrug transporter MdtD | + | + | + | + |
Probable RND efflux membrane fusion protein | + | + | + | + |
Response regulator BaeR | + | + | + | + |
Sensory histidine kinase BaeS | + | + | + | + |
Conserved uncharacterized protein CreA | + | + | + | + |
Inner membrane protein CreD | + | + | Â | Â |
Two-component response regulator CreB | + | + | Â | Â |
Two-component response regulator CreC | + | + | Â | Â |