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Fig. 6 | BMC Microbiology

Fig. 6

From: Nystatin enhances the immune response against Candida albicans and protects the ultrastructure of the vaginal epithelium in a rat model of vulvovaginal candidiasis

Fig. 6

Ultrastructural changes in the vaginal epithelium infected with C. albicans in the untreated 15 d sub-group. a, The vaginal mucosa is extensively damaged and inflammatory cells have infiltrated the vaginal epithelium. Magnification × 3000. b, Karyolysis with dissolved chromatin (arrow) of the VECs. Magnification × 15,000. c, Desmosomes between adjacent epithelial cells destroyed and intercellular spaces widened. Magnification × 6000. d, Mitochondria in VECs significantly swollen with decreased matrix density and incomplete rupture of the inner and outer mitochondrial membranes (arrow). Magnification × 30,000. e, More yeasts (arrow) are observed in the epithelial cytoplasm. Magnification × 15,000. f, The yeasts (arrow) in VECs are of irregular shape and appear to reproduce by budding. Magnification × 30,000

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BMC Microbiology

ISSN: 1471-2180

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